Scientist III/IV (Non-PhD)
Position Title: Scientist III/IV Work Location: Ridgefield, CT 06877 Assignment Duration: 12 Months Key Responsibilities: Design, develop, and execute functional genomics assays, including CRISPR-based editing (e.g., RNP delivery, Perturb-seq), single-cell sequencing, spatial transcriptomics, and CITE-seq Provide technical guidance and training to research scientists on FGSL technologies and techniques, including assay execution, troubleshooting, and resolution of technical issues Documents and maintains detailed laboratory records in accordance with policies Operates and maintains lab equipment in collaboration with other lab members Assists acquisition of necessary supplies and equipment Defines and performs appropriate QC measures Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports Automate processing and results reporting and delivery Reports and treats data with a high level of integrity and ethics Qualification & Experience: CRISPR assays - Must have personally designed guides, performed transfections/infections, selected edited cells, and validated knockouts/knockins Next-generation sequencing (NGS) - Hands-on library preparation experience (not just data analysis) Single cell technologies - Personal experience with sample prep, library generation, and quality control Standard molecular biology techniques - qPCR, Western blot, cloning, gel electrophoresis Cell culture - Proficient in maintaining multiple cell lines, transfections, and sterile technique Experience in automation is a plus Able to perform variety of FGS experimental techniques at the same time Demonstrated experience working in a multi-disciplinary and collaborative environment Ability to troubleshoot FGS experiments both individually and as part of a team Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner Master’s degree from an accredited institution with 6 years of experience in molecular, cell biology, or related scientific discipline Additional Notes from HM – Must have 2 years of Crispr experience. Molecular biology, qPCR, western blot. Proficiency in cell culture. Primary cell lines. Design guide RNA for a target, order a guide RNA, do the cell culture, grow cells, they do the electroporation, coordinate CRO work, submit samples on behalf of other Tas. Them teach them single-cell-seq Everyday will be cell culture work; QPCR, western blot Applicant Notices & Disclaimers For information on benefits, equal opportunity employment, and location-specific applicant notices, click here At SPECTRAFORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position's starting pay is: $50.00/hr. Key Responsibilities: Design, develop, and execute functional genomics assays, including CRISPR-based editing (e.g., RNP delivery, Perturb-seq), single-cell sequencing, spatial transcriptomics, and CITE-seq Provide technical guidance and training to research scientists on FGSL technologies and techniques, including assay execution, troubleshooting, and resolution of technical issues Documents and maintains detailed laboratory records in accordance with policies Operates and maintains lab equipment in collaboration with other lab members Assists acquisition of necessary supplies and equipment Defines and performs appropriate QC measures Follows relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may propose new avenues of investigation Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and technical reports Automate processing and results reporting and delivery Reports and treats data with a high level of integrity and ethics
