Principal Scientist – Translational Medicine (Tumor Microenvironment)

The Position We advance science so that we all have more time with the people we love. The Principal Scientist in Translational Medicine Oncology will support one or more translational programs contributing to the clinical development of oncology therapeutics. The successful candidate will be a key member of the Translational Medicine subteam, designing, developing, and implementing pharmacodynamic and predictive biomarker strategies across early- and late-stage clinical trials. This role also includes developing and leading hypothesis-driven translational research focused on identifying and developing novel biomarkers of therapeutic response and resistance, as well as uncovering disease-specific mechanistic insights. The candidate will collaborate closely on cross-functional biomarker efforts, working with colleagues across Research, Clinical Development, Diagnostics, Computational Science, Clinical Pharmacology, Regulatory, and Biostatistics. Strong scientific communication and collaboration with both internal and external stakeholders—including key opinion leaders (KOLs) and academic partners—will be critical to advancing translational objectives and disease area strategies in oncology. The Principal Scientist will also contribute to the scientific community through impactful publications and presentations at national and international conferences. We are particularly interested in highly motivated scientists with strong postdoctoral training who are excited to help bridge discovery science and clinical development in oncology. Prior industry drug development experience is not required. The Opportunity As a member of the Translational Medicine team, you will: Develop and execute biomarker strategies for oncology therapeutics from first-in-human through registrational clinical studies. Partner cross-functionally with Research, Clinical Development, Clinical Pharmacology, Biostatistics, Regulatory, and Companion Diagnostics to ensure scientific alignment and enable data-driven decision-making. Contribute to cross-functional project teams, ensuring alignment with overall program goals, timelines, and translational objectives. Develop and deploy next-generation biomarker assays across clinical programs to support development decisions and translational research efforts in oncology. Design and implement translational research plans leveraging clinical samples, multi-omic profiling, spatial biology, single-cell technologies, functional immune assays, and emerging AI-enabled analytical approaches, including agentic AI tools, to uncover mechanisms of response, resistance, tumor microenvironment interactions, and disease evolution. Contribute mechanistic understanding of tumor microenvironment dynamics and immune engagement to inform development and translational strategies for next-generation oncology therapeutics, including T cell engager approaches. Work closely with computational, translational, and laboratory scientists to integrate complex biological datasets and generate clinically actionable insights. Communicate project progress, challenges, and opportunities to leadership and stakeholders through presentations and written reports. Write and review biomarker- and disease-related sections of clinical protocols, study reports, regulatory documents, abstracts, and manuscripts. Contribute to external scientific engagement through collaborations and advisory interactions with academic investigators, clinical trialists, and biomarker experts. Publish impactful research in leading scientific journals and represent the organization at scientific and medical conferences worldwide. Who You Are: PhD, MD, or MD/PhD in molecular biology, cancer biology, immunology, computational biology, bioinformatics, or a related field. Strong expertise or scientific interest in tumor microenvironment biology and prostate cancer is preferred. Demonstrated scientific excellence through impactful graduate or postdoctoral research, including first-author publications in high-quality peer-reviewed journals. 3-5 years of experience with translational research approaches including molecular profiling, multi-omic analyses, spatial biology, single-cell technologies, and/or functional immune assays is preferred. Familiarity with computational approaches for biological data analysis; knowledge of R and/or Python is preferred. Interest in leveraging innovative computational approaches, including emerging AI-enabled and agentic AI tools, to support biomarker discovery, translational insight generation, and data interpretation is a plus. Strong scientific curiosity with the ability to independently develop hypotheses and translate complex biological observations into mechanistic insight. Excellent written and verbal communication skills, with the ability to communicate complex scientific concepts to multidisciplinary audiences. Ability to thrive in a collaborative, fast-paced, shifting priorities, and highly dynamic research environment. Demonstrated ability to collaborate effectively across diverse scientific disciplines and contribute positively to team culture. Relocation benefits are not available for this job posting. Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week. The expected salary range for this position based on the primary location of California is $141,500 - $262,900 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. J-18808-Ljbffr

Principal Scientist, Research (Targeted Delivery)

Key Responsibilities Lead design and implementation of innovative immunization strategies, including identifying, selecting, and managing external immunization vendors (CROs). Establish and oversee high-throughput B cell screening and selection workflows. Develop and integrate robust Next-Generation Sequencing (NGS) workflows to rapidly identify and analyze antibody variable region sequences from screening campaigns. Design, execute, and automate high-throughput screening cascades to characterize antibody properties (affinity, specificity, function). Engineer complex antibody modalities (multispecific antibodies, nanobodies) and evaluate novel protein formats. Collaborate with cross-functional teams (protein science, pharmacology, translational science) to achieve project goals. Manage project timelines, resources, and data analysis; present findings to internal teams and senior leadership. Qualifications PhD in Molecular Biology, Bioengineering, Biochemistry, Cell Biology, or related field. 6 years post-PhD biopharmaceutical industry experience focused on antibody discovery and engineering. Proven track record leading antibody discovery programs from inception to lead candidate delivery. Hands‑on single B cell isolation and screening; direct experience with Bruker Beacon platform required. Deep expertise in antibody cloning, expression, and sequence analysis; extensive experience with NGS library preparation and data interpretation. Experience developing and running high-throughput, automated screening assays. Experience managing external collaborations and CROs for immunization and discovery campaigns. Track record managing and developing research scientists (preferred). Location / Work Setup Onsite; primarily located in Cambridge, MA. Benefits Medical, dental, and vision Life and disability insurance Lifestyle reimbursement Flexible spending/HSA 401(k) with generous match Paid time off, wellness days, holidays, and two recharge breaks J-18808-Ljbffr

Police Lieutenant (Administrator II)

Apply now Job no: 551535 Work type: Management (MPP) Location: Sonoma Categories: MPP, At-Will, Full Time, Safety, On-site (work in-person at business location) Position Description Application Process This position is open until filled. For full consideration, please submit an application, along with a cover letter, resume, and response to the following supplemental questions by 8am on Friday, October 31, 2025. As a law enforcement professional, how would you promote and institutionalize the principles of procedural justice within the department, while ensuring that all operations and enforcement strategies are aligned with constitutional policing standards? Please provide an example of how you would lead this in practice, particularly in high-stakes or community-sensitive situations. Recognizing the unique dynamics of a diverse academic environment, please discuss your experience in building cooperative relationships, promoting community engagement, managing collaborative projects, completing or overseeing complex reports or initiatives and leveraging technology to enhance safety. This position requires successful completion of a written examination, oral interviews, pass an extensive background investigation in compliance with the requirements mandated by the California Commission on Peace Officer Standards and Training and current law, as well as a potential polygraph or similar examination, and a psychological examination, and medical exams which include a physical agility test and drug screening. Please review the position description listed above for full scope of responsibilities and qualifications. Evidence of degree(s) or certificate(s) and/or license(s) required at time of hire. Job Summary Reporting to the Chief of Police, the Police Lieutenant oversees patrol, investigations, community engagement, special events, records, policy, and training for the Sonoma State Police Department. The role includes managing and mentoring personnel, ensuring compliance with laws and CSU policies, and developing law enforcement programs and procedures. The Lieutenant collaborates with campus and external partners on mental health, investigations, task forces, threat assessments, manages incidents and events in the field, and assumes command in the Chief’s absence. Key Qualifications Minimum Qualifications: A Bachelor’s Degree or higher from an accredited higher education institution; and, Must be currently employed or previously employed in a California law enforcement agency as a Police Sergeant or higher with at least three (3) years of service at the rank of Police Sergeant; and, Possession of California P.O.S.T. academy, Basic, Intermediate, Advanced and Supervisory certificates; and, Ability to successfully earn the P.O.S.T. management certificate by completing a P.O.S.T certified management course within one (1) year of appointment and serving as a lieutenant for a period of two (2) years; and Meet all other requirements for peace officers, as established by law, the California Commission of Peace Officer Standards and Training, and the California State University; and, Must be at least 21 years of age except as provided by Government Code §1031.4; be legally authorized to work in the United States under federal law; and, Must possess and maintain a California class C Driver’s License valid for the operation of any vehicle or equipment required to maintain and operate. The incumbent will be required to enroll in the California DMV Employer Pull Notice Program. Preferred Qualifications: Experience in higher education, preferably with the California State University. Strong knowledge of law, and University policy and regulations regarding public safety and law enforcement functions. Strong knowledge of budgeting and financial practices applicable to law enforcement in a university environment. Intermediate proficiency with computers and Microsoft Office (Word, Excel) including knowledge of Google Suite and PeopleSoft. Strong communication and interpersonal skills and the ability to mentor, coach and develop others to achieve goals and objectives. Demonstrated ability to work collaboratively with a very diverse community. Salary and Benefits Starting salary placement depends on qualifications and experience and is not expected to exceed $13,334 a month. This position is a member of the Management Personnel Plan and serves at the pleasure of the President. This position is eligible for a broad range of benefits, including medical, dental, vision, life and disability insurances, retirement (CalPERS), tuition waiver, vacation and sick leave. In addition, 15 paid holidays are offered each year. Sonoma State University is also a Public Service Loan Forgiveness Program (PSLF) Employer. A comprehensive benefits summary for this position is available online by clicking here to be taken to the CSU benefits page. Supplemental Information Sonoma State University is committed to achieving excellence through teaching, scholarship, learning and inclusion. In line with our Strategic Plan and our Seawolf Commitment, our values include diversity, sustainability, community engagement, respect, responsibility, excellence and integrity. We strive to cultivate a community in which a diverse population can learn and work in an atmosphere of civility and respect. We encourage innovation, experimentation and creativity, as well as contributions to equity and inclusion, in the pursuit of excellence for all members of our university community. The University is an Affirmative Action/Equal Opportunity Employer. We consider qualified applicants for employment without regard to race, religion, color, national origin, ancestry, age, sex, gender, gender identity, gender expression, sexual orientation, genetic information, medical condition, disability, marital status, or protected veteran status. Mandated Reporting: This position may be considered a 'mandated reporter' under the California Child Abuse and Neglect Reporting Act and is required to comply with the requirements set forth in CSU Executive Order 1083 as a condition of employment. CSU Out of State Policy - Sonoma State University, as part of the CSU system, is a State of California Employer. As such, the University requires all employees upon date of hire to reside in the State of California. As of January 1, 2022 the CSU Out-of-State Employment Policy prohibits the hiring of employees to perform CSU-related work outside the state of California. A background check (including a criminal records check) must be completed satisfactorily before any candidate can be offered a position. Failure to satisfactorily complete the background check may affect the application status of applicants or continued employment of current employees who apply for this position. Sonoma State University is not a sponsoring agency for staff positions (i.e. H-1B visas). For questions related to the application process, please reach out to [email protected] . The ADA Coordinator is also available ([email protected] ) to assist individuals with disabilities in need of accommodation during the hiring process. Sonoma State University's Annual Security Report includes summaries of institutional policy relating to campus safety, drug and alcohol use, sexual assault, and other matters. The report is published in compliance with the Clery Act and includes three years of certain crime statistics that occurred in Clery Act defined geography. A paper copy of the report may be requested in person by emailing the Clery Compliance and Safety Office at [email protected] . Pursuant to the Higher Education Opportunity Act, the Annual Fire Safety Report (AFSR) is available for viewing at https://housing.sonoma.edu/compliance-data/2024-campus-housing-fire-safety-report . The purpose of this report is to disclose statistics for fires that occurred within Sonoma State University student housing facilities for three years, and to distribute fire safety policies and procedures intended to promote safety on campus. A paper copy of the AFSR is available upon request by contacting the Residential Education and Campus Housing at [email protected] . Advertised: October 02, 2025 (9:00 AM) Pacific Daylight Time J-18808-Ljbffr

Freight Dispatcher (Independent Contractor) — $1,800 to $4,500 Weekly Potential

Freight Dispatcher (Independent Contractor) — $1,800 to $4,500 Weekly Potential Employment Type: 1099 / Independent Contractor Location: Remote (U.S. Based Only) This is a performance-based dispatch role working with owner-operators under their own authority. Earnings are commission-based , and income depends on efficiency, negotiation skill, and carrier volume. What You’ll Do Book loads through broker networks and load boards Negotiate competitive rates Coordinate pickups, deliveries, tracking, and paperwork Communicate professionally with both drivers and brokers Manage your workflow independently Requirements Must currently reside in the U.S. Laptop or desktop computer High-speed internet connection Professional phone / headset Organized, dependable, and self‑motivated Experience in dispatching, brokerage, customer service, or similar communication-based roles is beneficial but not required. What’s Provided Training resources and support systems Workflow templates and operational guidance Options for sourcing owner-operators to dispatch Structured performance incentive program based on results (not a guaranteed or upfront bonus) Who This is For People who: Prefer commission-based income with high earning potential Can stay organized without supervision Want to control their schedule and growth How to Express Interest Submit your application or response through the platform where this listing is posted. A brief screening will follow to confirm fit and onboarding readiness. J-18808-Ljbffr

Global Head of Sales - Tec4Med

Cryoport Systems is the life science industry’s most trusted provider of supply chain solutions for temperature‑sensitive materials, serving biopharmaceutical, IVF and surrogacy and animal health organizations around the world. Cryoport Systems' proprietary Cryoport Express® shippers, Cryoportal® Logistics Management Platform, leading‑edge Smartpak™ Condition Monitoring System and geo‑sensing technology paired with unparalleled logistics expertise and 24/7/365 customer support, make Cryoport Systems the end‑to‑end temperature controlled supply chain partner that you can trust. POSITION SUMMARY The Global Head of Sales owns Tec4med's worldwide revenue strategy and execution. This leader will design, build, and scale a high‑performing sales organization across regions, with a strong initial focus on Europe and the United States. This is a hands‑on leadership role requiring strategic thinking, operational excellence, and direct involvement in key enterprise deals. You will work closely with the CEO, product, and marketing teams to translate Tec4med's technology into sustainable global revenue and EBITDA growth. PRIMARY RESPONSIBILITIES (include but are not limited to)Sales Strategy & Revenue Ownership Define and execute the global sales strategy aligned with company growth objectives Own global revenue targets, forecasting, and pipeline health Establish scalable sales processes from lead qualification through contract close Develop pricing and commercial models for enterprise and mid‑market customers Go‑to‑Market & Market Expansion Lead market entry and expansion strategies, particularly in the US market Identify priority verticals (pharma, biotech, CDMO/CRO, Animal Health, IVF, healthcare logistics) Build strategic partnerships and channel relationships where applicable Work with marketing to refine messaging, positioning, and demand generation Sales Organization & Leadership Build, hire, and mentor a global sales team (BD, AE, regional leads) Define roles, KPIs, compensation structures, and incentive plans Create a strong sales culture focused on accountability, execution, and customer value Act as a coach and deal‑closer for opportunities Enterprise Sales & Key Accounts Personally lead or support strategic enterprise deals and local / global tenders Build relationships with senior decision‑makers at global pharma and healthcare organizations Negotiate complex commercial agreements and long‑term contracts Ensure customer expectations are aligned with product and delivery capabilities Cross‑Functional Collaboration Act as the commercial voice in product roadmap discussions Provide structured market feedback to product and leadership teams Align sales, customer success, and operations for smooth onboarding and retention Ensure CRM discipline, reporting accuracy, and sales analytics maturity to the C‑Level Peer‑level collaboration with sister companies’ sales leadership, including Cryoport Systems, MVE, and CryoGene Develop and execute cross‑company sales strategies to leverage complementary portfolios and shared customer bases Coordinate joint go‑to‑market initiatives, account strategies, and commercial positioning across group entities Align sales activities to avoid channel conflicts and maximize group‑wide revenue opportunities Enable knowledge sharing and best practices across sales organizations within the group Represent Tec4med in group‑level commercial discussions, reporting and initiatives COMPETENCIES & PERSONAL ATTRIBUTESCommercial & Strategic Competencies Revenue leadership: strong ownership mindset for global revenue, forecasting, and performance Go‑to‑market excellence: ability to design, execute, and iterate GTM strategies across regions Enterprise deal‑making: skilled in complex, multi‑stakeholder B2B sales cycles Market insight: deep understanding of customer pain points in regulated healthcare environments Data‑driven execution: uses metrics, KPIs, and CRM data to drive decisions and accountability Scalability mindset: builds repeatable, scalable sales processes rather than one‑off wins Proven experience operating as a peer among senior sales leaders across sister companies High emotional intelligence and political acumen to manage cross‑company dynamics Credibility to challenge, align, and drive decisions at executive level without formal reporting lines Leadership & Organizational Skills Builder mentality: comfortable creating teams, structures, and processes from scratch Growth mindset: continuously seeking feedback, learning from outcomes, and evolving strategies to improve individual, team, and group‑wide sales performance People leadership: proven ability to hire, coach, and retain high‑performing sales talent Cross‑functional influence: works effectively with product, marketing, operations, and leadership as well as all Cryoport Inc. sister companies Executive presence: confident communicator with credibility at C‑level and board level Decision‑making under ambiguity: able to lead with incomplete information in fast‑moving environments Personal Attributes Hands‑on and pragmatic: willing to engage directly in deals, customer conversations, and execution Ownership‑driven: acts like an owner, not a passenger Resilient and persistent: comfortable with long sales cycles and regulated customer environments Customer‑centric: focused on long‑term value creation, not short‑term transactions Mission‑aligned: motivated by improving safety, transparency, and compliance in healthcare QUALIFICATIONS AND EDUCATION REQUIREMENTSRequired 10 years of B2B sales experience, with at least 5 years in a senior sales leadership role Proven track record of building and scaling international sales organizations Strong experience selling complex B2B solutions (MedTech, IoT, SaaS, or regulated industries) Demonstrated success closing enterprise and multi‑year contracts Deep understanding of pharma, biotech, medical devices, or healthcare logistics markets Experience selling into regulated environments (FDA, GMP, GDP, MDR) Willingness to travel internationally Preferred Experience scaling revenue from early‑stage to growth‑stage US market entry and scaling experience Background in IoT, digital health, or supply‑chain technology Experience working in European / US cross‑border organizations Cryoport, Inc. is redefining temperature controlled supply chain support for the life sciences industry by continually broadening its platform of solutions, serving the biopharma, reproductive medicine and animal health markets. Through its family of companies — Cryoport Systems, MVE Biological Solutions and Cryogene — Cryoport provides strategic solutions that will support the growing needs of these markets. J-18808-Ljbffr