Senior Medical Director, Hypertension (Wilmington)

Location: Wilmington Hybrid: 3 Days a week At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. About the Role The Senior Medical Director, Hypertension shapes product and disease area strategy, provides strategic direction for evidence generation, education and publication, and engages extensively externally to further the scientific leadership of AZ. It is a key scientific role that reports directly to the Medical Head – Hypertension, within the BioPharmaceuticals Business Unit’s US Medical CVRM franchise. What you’ll do: Provide medical leadership and subject matter expertise for the creation, delivery and evolution of disease area and brand strategies and plans Build external collaborations (e.g. relationships with KEEs, investigators, scientific associations, digital therapeutics/diagnostics partners) and seek and incorporate external advice to drive strategy Lead the product and disease area Advisory Board strategy Lead the product and disease area Externally Sponsored Research (ESR) program Shape and drive strategic publications plans and evidence-generation initiatives Provide medical leadership and subject matter expertise for regulatory and labelling interactions Through partnership and innovative thinking, anticipate future trends and needs in the marketplace Essential for the role: MD, PhD, or PharmD Medical/clinical/scientific expertise in CVRM 5 years of experience in the pharmaceutical industry, ideally in Medical Affairs or relevant years of experience in the Medical / Healthcare field Strategic and innovative thinker with an executive presence Demonstrated track record delivering results in a complex matrix environment, building capabilities, and leading large-scale impactful medical initiatives Proven ability to collaborate and build internal and external networks Strong analytical mindset and ability to quickly assess large amounts of information and distil into key messages and actions Experience and/or appreciation of product launches and product life cycle management Persuasive oral and written communication skills, including the ability to develop and deliver impactful presentations Proven ability to collaborate with individuals of diverse experience and backgrounds, across varying functions, levels within the company, or external organizations, to effectively deliver on goals Strong business acumen, familiarity with the US healthcare system, and key regulations in the pharmaceutical industry The annual base pay for this position ranges from $243,586.40 - $365,379.60 USD Annual USD Annual and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Date Posted 17-Aug-2026 Closing Date 27-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. J-18808-Ljbffr

Senior AI Security Solution Architect (New York)

What You Will Do 7 years Design and build an agentic vulnerability-discovery harness from end to end. Architect the agent runtime, orchestration layer, and parallel vulnerability-hunting agents. Develop adversarial validation workflows that verify candidate findings before publication. Build cross-repository indexing, dependency mapping, and source-to-sink reachability analysis capabilities. Establish isolated execution environments for exploit validation. Validate the platform against labeled vulnerability datasets and measure detection quality. Publish validated findings into Azure DevOps using SARIF. Create runbooks, hardening guides, and production-readiness documentation. Required Qualifications Production experience building LLM agent or multi-agent systems. Experience with agent orchestration, tool integration, evaluation loops, and non-deterministic model behavior. Strong software architecture and engineering experience. Preferred Qualifications Application security, vulnerability discovery, and exploit development. CodeQL, Semgrep, Joern, taint analysis, and data-flow analysis. Tree-sitter, SCIP, or LSP-based indexing. Firecracker, gVisor, or similar isolated execution platforms. SARIF and Azure DevOps integration experience. Technology Environment LLM Agent Frameworks: LangGraph, Bedrock AgentCore, MCP-based tooling Security Analysis: CodeQL, Semgrep, Joern, SAST, SCA Isolation Technologies: Firecracker, gVisor, Containers DevOps & Security Operations: Azure DevOps, SARIF, CI/CD Security Pipelines About Vertical Relevance Vertical Relevance was founded to help business leaders drive value through the design and delivery of effective transformation programs across people, processes, and systems. Our mission is to help firms at any stage of their journey develop custom solutions for success and growth. We provide a full range of services from strategy and design through to implementation and training. Our collective industry expertise is our greatest asset - our professionals have an average of 20 years’ experience within Financial Services, across Wealth Management, Asset Management, Insurance, and Banking. Within our Customer Experience practice, we add complementary industry expertise (technology and media) synergizing the most relevant and successful customer trends. We focus wholly on your success by first rigorously assessing your business and technology challenges, and then right-sizing solutions that provide a meaningful ROI. With our industry experts hitting the ground running and focusing on nimble, quality delivery, we can see rapid, tangible improvements with our clients in productivity and effectiveness. When it makes sense for your company, we leverage our product partnerships in the areas of CRM, Sales Acceleration, Predictive Analytics, Digital Knowledge Management, and Cloud Transformation. J-18808-Ljbffr