Senior Director, Drug Product CMC (Boston)

Centessa is seeking an Senior Director of Drug Product within the CMC group. The successful candidate will have a demonstrated, proven track record of designing high performance nonclinical and clinical formulations as well as managing CROs and CDMOs. The candidate should also have hands‑on experience in developing and manufacturing nonclinical and clinical small molecule drug products to support Phase I to Phase III. Description Of Role Reporting to the Executive Director, CMC, this position will primarily lead work with external vendors and oversee nonclinical formulation development, with flexibility to support clinical drug product development, across programs to meet company deliverables and timelines. Travel to domestic and international vendors required. Key Responsibilities Directly manage external vendors, such as Contract Research Organizations (CROs) and Contract Development and Manufacturing Organizations (CDMOs) to: Execute physiochemical characterization and pre-formulation studies for New Chemical Entities (NCEs). Design and develop nonclinical formulations of drug candidates (oral, subcutaneous, and intravenous) to ensure stability, bioavailability and effective drug delivery in animal models. Design and oversee execution of nonclinical formulation stability and compatibility studies. Support clinical formulation development of oral solid dosage forms, as needed. Author and/or review and approve development and dose preparation protocols and reports. Review formulation related sections of protocols and reports associated with Pharmacokinetic (PK), Pharmacodynamic (PD), and safety studies. Represent CMC and provide nonclinical formulation, DS and DP stability, and supply guidance at internal and external cross functional team meetings. Coordinate shipments in support of nonclinical and Clinical development supply requirements to various CDMO and CRO sites. Assist in compiling formulation-related documentation for regulatory submissions (e.g., IND, CTA) to meet nonclinical development requirements. Work closely and collaboratively with cross-functional CMC groups including discovery, nonclinical, clinical, project management, legal, sourcing, supply chain, quality and regulatory, as well as other CMC functions. Qualifications Advanced degree in Chemistry, Pharmaceutical Sciences, or a related discipline; Ph.D. strongly preferred. 10 years of drug product/formulation development experience supporting nonclinical and clinical programs, with expertise across oral, subcutaneous, and intravenous dosage forms for small molecules. Deep technical expertise in the development and manufacture of poorly soluble (BCS Class II/IV) compounds, including formulation strategies for oral and parenteral delivery. Strong understanding of pharmaceutical sciences and engineering principles related to liquid and solid dosage form development from early-stage development through clinical and commercial manufacturing. Working knowledge of analytical and solid-state characterization techniques, including HPLC/UPLC, XRPD, DSC, TGA, DVS, and related methodologies. Experience managing external development and manufacturing partners (CROs, CDMOs, and CMOs) and a solid understanding of cGMP requirements. Proven ability to lead multiple complex programs in a fast-paced environment, with strong project management, prioritization, resource management, and organizational skills. Excellent communication, presentation, and interpersonal skills, with the ability to influence stakeholders, build productive internal and external partnerships, and communicate complex scientific concepts to diverse audiences. Strategic, hands‑on leader with strong decision‑making and problem‑solving capabilities, demonstrated resilience, and a track record of delivering high-quality results with urgency and integrity. Willing and able to travel domestically and internationally as needed. Compensation The annual base salary range for the Sr. Director level position is $165,000.00 to $250,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, job knowledge and location. In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program. Work Location The (Senior) Director Drug Product CMC role is based in the US, with occasional travel. POSITION Full-Time, Exempt EEOC Statement Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Please note We will not assign referral rights for any unsolicited resumes from recruitment agencies. J-18808-Ljbffr

Director, Hardware Engineering (South Jordan)

Department: Product and Hardware Engineering Company Description Cricut® empowers people to make and personalize almost anything—from custom cards and apparel to everyday items and home décor. Our smart cutting machines, design apps, and materials make creativity easy and accessible for everyone. We believe everyone is born creative, and our mission is to put the power of handmade into the hands of all. With a passionate community of Makers around the world, Cricut helps turn inspiration into real, tangible creations—one project at a time. Let’s make. Job Description Job Description Cricut is looking for a Director of Hardware Engineering who understands what it takes to make great products. This individual will be technically competent, passionate aboutthe consumerexperienceand proficientatproduct development. You will be adept at developing a collaborative and highly competent engineering team where engineering creativity and passion can thrive. As a leader at Cricut you will be involved in and understand thedetails, buthave a broader perspective to helpidentifyand mitigate risks and issues that could inhibit our various projects and teams. To besuccessfulyou will be a high performer with a rare and specific skill set who will thrive in a fast-paced and demanding environment. Your ability to think critically, lead through intellect, bring out the best in your team, and to partner across a wide variety of functions at Cricut to drive change in a complex setting will be essential to the rollout of our offerings to the market. Key responsibilities include: Help set and manage priorities among competing projects Hire engineers and project managers that are humble, hungry, and smart, and develop them into high performing teams that imbue the culture of Cricut into our products. Mentor the team in key aspects of product developmentincluding:Risk Assessment, Project Planning, Troubleshooting & Root CauseIdentificationand Incident Management. Assistin developing the technology and product roadmap. Participate in identification and evaluation of new manufacturing partners Assistin the development of annual budgets Partner with ID, UX, Product Management, SW and other organizations in the successful design and development of new products Workhand-in-handwith Product Management throughout the development process, understanding the user needs and productobjectives, while making sure they understand the development status,issuesand challenges for the product Provide technical inputregardingnew and evolving product opportunities Research and contribute ideas for new opportunities to help people lead creative lives Help tomaintaina database of product and tooling costs that can be used as a benchmark against future development efforts. Help projectteams towork through critical issues and develop alternative actions to overcome the issues andmaintainthe schedule. Be involved in the prototyping, pre-productionand mass production of new or transferred products. Cultivate the Cricut Values both within the engineering team and throughout the organization Qualifications As a minimum, must have abachelor's degree in Engineering, Mechanical Engineering strongly preferred with a working knowledge of electro-mechanical systems Strong technical aptitude and hands on management experience of a large team A proventrack recordas a team leader on complex projects The ideal candidate will have experience in consumer product development. 5 years in project management related to product development Strong communicationskills,team workand interpersonal skills Strong analytical andproblem solvingskills Adept at Microsoft Project, MS Excel. Proficiencyin Minitab highly desirable The ability to understand, apply, and mentor engineers in statistical process control methods is highly desirable including CPKs, T-Tests, X-Bar/R charts, DOEs, etc. Additional Information At Cricut, we take care of our people. Enjoy competitive Medical, Dental, and Vision coverage, a 401(k) match, generous PTO, tuition reimbursement, and a yearly lifestyle stipend to support your wellness and passions. You’ll also receive exclusive employee discounts—and best of all, you’ll be surrounded by some of the most talented, creative, and curious minds out there. A Quick Note Before You Apply… Cricut is in an exciting chapter of transformation. We’re evolving fast—refining our strategy, growing our teams, and raising the bar across everything we do. This is an incredible opportunity for the right kind of person—but it’s not for everyone. We’re looking for A-players—people who thrive in dynamic environments, turn challenges into momentum, and consistently deliver their best work. If that sounds like you, read on. Here’s what makes someone a great fit for this role (and for this moment at Cricut): You move with urgency. You don’t wait for perfect clarity to act—you start, learn, and adjust. You set high standards. You take ownership, deliver quality, and hold yourself accountable. You stay focused when things move fast. You prioritize what matters most and tune out the noise. You collaborate like a pro. You elevate others, communicate clearly, and bring a low-ego, high-output energy. You embrace AI as part of your toolkit. From idea exploration to data analysis and creative problem-solving, you leverage AI to accelerate innovation and amplify impact—because technology and creativity go hand-in-hand here. One More Thing (It’s a Big One) This role is in-office at least 4-5 days per week. We believe real collaboration, innovation, and culture are built face-to-face. If you’re energized by working alongside smart, kind, creative people—and love those hallway conversations that spark the next great idea—you’ll feel right at home. If you’re looking for a fully remote role, this may not be the right fit. But if you’re excited by challenge, purpose, and building something better—let’s make something amazing together. Relocation Statement: This position is eligible for relocation assistance. Cricut® is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. This position is contingent on successfully completing a Criminal Background Check upon hire. Cricut participates in E-Verify. J-18808-Ljbffr

Deputy Chief Operating Officer (Menlo Park)

SLAC is operated by Stanford University for the U.S. Department of Energy’s Office of Science and is one of 17 DOE national laboratories - the most comprehensive research system of its kind in the world, providing strategic scientific and technological capabilities and expertise that cannot be found elsewhere. A major part of the Office of Science mission is supporting the development, construction, and operation of unique, open-access scientific user facilities. The laboratory is home to three Office of Science user facilities: the Linac Coherent Light Source, the Stanford Synchrotron Radiation Lightsource and the Facility for Advanced Accelerator Experimental Tests. SLAC sits on 426 acres of Stanford land, located two miles from the main university campus. The lab’s ties with Stanford have grown over the years to include several joint institutes and facilities and many collaborative research efforts. Stanford has made numerous investments in the laboratory and provides key services that make its operations more efficient. SLAC also plays a key role for Stanford, which benefits from the lab’s deep expertise in key areas and its ability to develop and run large-scale research facilities. Together with Stanford, SLAC educates and develops the U.S. scientific workforce in key technological areas. Position overview Provides support to the Deputy Laboratory Directory for Operations and Chief Operating Officer (COO) in the leadership, development and implementation of strategic plans, policies, and operational responsibilities. Partners with the programmatic areas of the laboratory to advance world class operations support of the scientific mission of the laboratory. Responsible for engaging stakeholders, defining requirements, and implementing assigned laboratory-wide programs.Acts on behalf of the Deputy Laboratory Directory and COO in their absence and is a delegate for authorized approvals. Provides strategic budget support for the COO’s approval that efficiently and effectively delivers the services that are needed and align with the SLAC mission. Provides support in regard to development of initiatives and encourages innovation and continuous improvement throughout the laboratory complex. Develops and maintains relationships with Department of Energy, Stanford University, and various other stakeholders in the formulation of crosscutting programs, initiatives, and solutions. Possesses the ability to listen and consult with a wide range of stakeholders and recognize and resolve operational issues of the Laboratory through multi-disciplinary teams that crosscut the Laboratory. Supports and helps advocate talent management strategies that advance a diverse and inclusive workforce. The successful candidate will also need to be able to uphold and demonstrate SLAC’s Core values: Excellence, Integrity, Collaboration, Respect, Creativity, on a daily basis. Your specific responsibilities include Provide strategic leadership and management of administrative and operational functionsexercising delegated authority for policy and programmatic decisions. Achieve goals through managerial staff; typically have multiple levels of professional and supervisory staff. Oversee the management of areas of responsibility. Direct staff and provide leadership to achieve goals and vision of the organization. Responsible for hiring and retaining staff, career coaching, personal development for direct reports and accountable for the performance of employees. Provide strategic direction for multiple areas of business; create strategic plans of considerable complexity and scope; set long range direction and make high level decisions; propose and manage the implementation of complex and significant programmatic change; establish policies as needed. Make decisions for programs that provide critical support services for the Laboratory. Oversee allocation of all assigned resources. Set the direction of an organization and direct the policy development and implementation of administrative operations and workforce planning. Evaluate the performance of the organization and develop plans accordingly. Responsible for the financial viability and success of the organization. Responsible for committing resources with limited review by senior management. Advise executive management on programmatic and policy development. Negotiate and influence Laboratory leaders on issues that have Lab-wide impact. Champion major initiatives, J-18808-Ljbffr

General Counsel (Palo Alto)

About Arc Institute Arc Institute is an independent nonprofit research organization at the interface of artificial intelligence and biology, working to accelerate scientific progress and understand the root causes of complex diseases. Founded in 2021 and based in Palo Alto, Arc partners with Stanford University, UC Berkeley, and UC San Francisco. Unlike academia, our scientists have long-term funding and industry-like resources. Unlike industry, they're free to pursue high-risk, long-term research without commercial pressures. Arc's Technology Centers and Core Investigator labs work side by side, integrating experimental and computational biology under one roof to tackle problems neither could solve alone. Our two Institute Initiatives reflect this model in action: Virtual Cell Initiative : Building a full-stack virtual cell model to identify disease mechanisms and nominate drug targets, accelerating the path from biological insight to clinical trials. Alzheimer's Disease Initiative : Mapping the genes, pathways, and environmental factors behind Alzheimer's disease to develop drug candidates that address root causes. More than 300 Arconauts work together at our Palo Alto headquarters, backed by substantial long-term philanthropic funding. About the position Arc Institute is seeking a General Counsel to serve as a strategic legal advisor and trusted peer to leadership. Reporting to Co-Founder and Executive Director, Silvana Konermann, the General Counsel will help identify and execute the legal pathways that enable Arc to pursue ambitious scientific and institutional goals. This role requires a commercially sharp, highly proactive lawyer with strong judgment, excellent instincts, and the ability to move complex matters forward with urgency and rigor. About you A strategic, solutions-oriented lawyer who thrives on solving difficult problems and moving complex matters forward. Highly proactive, resourceful, and comfortable taking ownership in ambiguous environments. A fast learner who can quickly develop fluency in new scientific, operational, and institutional domains. A strong communicator who translates legal risk into practical advice and decisive next steps. Able to balance rigorous legal analysis with a strong bias toward action and outcomes. A collegial, trusted leader and peer who earns confidence quickly, contributes constructively, and helps teams make sound decisions. Confident engaging with senior leaders and external counterparties in high-stakes settings while maintaining professionalism, discretion, and good judgment. In this position you will Lead legal strategy for complex collaborations, partnerships, and institutional arrangements that advance Arc’s mission. Advise leadership on governance, compliance, conflicts, regulatory, and risk matters. Oversee legal agreements with academic, industry, nonprofit, and other strategic partners. Identify legal pathways that enable new initiatives while protecting the Institute’s interests. Support business development and strategic growth initiatives. Build and improve legal processes, policies, and frameworks that support speed, clarity, and responsible execution. Manage and develop a small legal team, which includes an existing IP & Licensing function, and supervise outside counsel as needed. Provide clear, practical, and independent counsel to senior operational and scientific leadership. Requirements JD and Active membership in the State Bar of California, or eligibility to practice immediately as Registered In-House Counsel in California. Experienced leader and member of an executive team Experienced people manager with track record of mentorship and skill development 15 years of relevant legal experience including significant experience in corporate, transactional, technology transfer, engineering, life sciences, or related legal work. Demonstrated ability to advise senior stakeholders on complex legal and strategic matters. Experience leading or materially supporting high-stakes negotiations and transactions. Preferred Qualifications Experience structuring novel or complex legal arrangements in innovation-driven environments. Experience managing a team of IP professionals or supervising external IP counsel. Experience in biotech, life sciences, technology, or similarly fast-moving sectors. The base salary range for this position is $330,000 to $450,000. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors. J-18808-Ljbffr

General Counsel (Fort Lauderdale)

Job Summary Blue Sky Utility/NofarUSA, a renewable energy development and operations company focused on large-scale solar and energy storage, is seekingaGeneralCounsel tolead our in-house legal function andserve astheseniorlegalauthorityfor the company.The General Counsel willoverseeandmentorourSenior Counsel,collaboratewithoutsidecounsel, as needed,andindependently manageour highest-complexityM&Atransactions,projectand corporate financing transactions, PPAs, offtake agreements,andrelatedregulatory matters. This is a Hybrid role with 3 days in office in our Fort Lauderdale office. Requirements Qualifications J.D. from an accredited law school,activeFlorida Barlicenseoractivebar admission in at least one U.S.jurisdictionwith theability tobecome licensed asauthorizedhouse counselin Florida. 10 years of experience in renewable energy law, withrequired prior in-house experience at an Independent Power Producer (IPP), developer, orutility.Law firm-only backgrounds will not meet the bar. Track recordofleading andowning,not justsupporting,complexM&A,project development,projectfinance, corporate finance, and offtake/transactionsfrom term sheet through closing, with minimalreliance on outside counsel. Substantial experience with project finance, tax equity, and/or M&A in the renewables space. Deep command of state-level utility regulatory frameworks, to the point of being a go-to internal resource on regulatory questions. Demonstrated experience drafting,negotiatingand advising oncomplex transaction and project agreements, including, but not limited to Membership Interests Purchase Agreements, Purchase and Sale Agreements,Joint Development and Joint Venture Agreements,Engineering, Procurement and Construction Agreements,Operation and Maintenance Agreements, Offtake Agreements,and Power Purchase Agreementsis required. Experience leading project financing, tax equity, securedfinancing,and other structured financing matters. Experience with capitalmarketstransactions, ongoing securities law compliance and reporting obligations is strongly preferredbut notrequired. Responsibilities Independentlydraft, negotiate and advise onhigh-value contracts and transactions: PPAs, EPCs, interconnection agreements, project financings,andM&A,andjoint ventures. Serve as a senior escalation point for legal questions fromthe rest ofthe legal team, includingexistingSeniorCounsel and paralegal staff. Directly absorba significant portionoftheSeniorCounsel's currentworkload. Build and own legal processes, templates, and playbooks that raise the operating level of the whole department. Manage outside counsel relationships and budgets for specialized/high-stakesmatters. Advise cross-functional and executive teams on regulatory strategy, not just compliance. Education Juris Doctor (J.D.) Benefits We offer medical, dental, and vision insurance, short-term disability, life insurance, and a 401(k) with a generous 6% company match. What We Offer We operate with a lean, highly capable team, which means there aren’t layers of people between you and the work that matters. You’ll have real ownership, direct access to decision-makers, and the opportunity to influence how we build and grow the business. If you want to be a meaningful voice rather than a small part of a very large machine, you’ll find that opportunity here. A Fast Pace and a High Bar We believe in being transparent about what it’s like to work here: we move quickly, the workload can be demanding, and our expectations are high. This is an environment for people who enjoy being challenged, solving problems, taking initiative, and figuring things out as we grow. In return, you’ll gain exposure, responsibility, and influence that can take years to earn in a more traditional organization. Who Thrives Here The people who do best at Blue Sky are proactive, resourceful, and comfortable taking ownership. They don’t wait to be told what to do next, and they’re willing to step outside the boundaries of a job description when the business needs it. They care about outcomes more than watching the clock, bring solutions instead of simply identifying problems, and genuinely enjoy the energy — and occasional ambiguity — that comes with building a growing company. If you’re a go-getter who wants room to run, you’ll fit in well here. Benefits That Invest in You We offer medical, dental, and vision insurance, short-term disability, life insurance, and a 401(k) with a generous 6% company match. Hybrid, With Purpose We believe there is real value in being together. Our hybrid model creates regular opportunities for in-person collaboration, faster decision-making, and stronger relationships while still providing flexibility outside of the office. What to Expect From Our Hiring Process We’re Choosy — On Purpose. Our typical hiring process looks like this: HR Screen → Hiring Manager Interview → Culture Assessment → Case Study, when applicable → Cross-Team Interview → CEO Meet & Greet → Offer Not every role requires a case study, but for certain positions we use one to better understand how you think, approach problems, and tackle the type of work you would actually be doing here. It Sounds Like a Lot. It Doesn’t Take a Lot of Time. We’re deliberate in our hiring decisions, but we’re also decisive. Our average turnaround from initial HR screen to offer is less than two weeks . We move quickly and respect that candidates have jobs, lives, and other opportunities in motion. You’ll Always Know Where You Stand. Clear communication is an important part of our candidate experience. We’ll be transparent about the process and expectations from the beginning, keep you informed as you move through each stage, and close the loop when a decision has been made. We believe every candidate deserves clarity and respect for the time they invest in getting to know us. We’re intentional about who joins our team because every person on a lean team has an outsized impact. When we make an offer, it’s because we’re genuinely excited about what you can bring to the team. J-18808-Ljbffr