Director, Pharmaceutical Sciences Program Leadership (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Objective / Purpose: Expected to engage others by inspiring commitment. Collaborate by influencing through relationships, mobilize high performance, anticipate the group’s future needs and help develop capabilities aligned with those needs. Champion change and be a role model for junior staff not only in technical expertise but across Takeda competencies. Independently leads development of strategy and plans for multiple, complex programs Regularly leads and influences functional/divisional strategy, operations and innovation Functional thought leader and mentor Impactful contributor to divisional initiatives and may contribute to corporate, cross-divisional, and global initiatives Accountabilities: Program Leadership : Provides strategic scientific leadership and program management for multiple global CMC development teams dealing with complex development programs that require scientific depth and overall product development acumen for successful execution Identifies, mitigates and communicates project or program risks to relevant stakeholders. This person is expected to advance not only the program teams they lead but also other teams that are facing unique challenges. Lead/participates as functional expert in divisional and cross-divisional initiatives. Represents CMC on cross-divisional governance and development teams while providing strategy and accountability for CMC deliverables. Technical Acumen : Provides scientific leadership and innovation in pharmaceutical research and development. Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives. Mentors other members of the department to develop their abilities to lead and advance their individual skills of pharmaceutical product development. Demonstrates humility and approachability in encouraging others to challenge ideas and openly raise issues. Acts as an internal consultant to the Pharmaceutical Sciences staff for any scientific advice that may be needed on a project basis. Develops the capabilities of the department by identifying opportunities and anticipating changes in the business landscape through an understanding and ongoing assessment of the environment affecting the business. Represents Pharmaceutical Sciences in cross divisional, corporate and global initiatives. Cultivates a broad network of relationships throughout Takeda, with affiliates and alliance partners, in the industry and area of expertise. Inspires commitment through a wide range of communication channels (meetings, writing, and presentations). Develops and communicates convincing business cases for department strategies that motivate stakeholders to take action. Ensures that technical and scientific standards within the function meet state-of-the-art industry expectations. Identifies, evaluates, develops, recommends and/or negotiates novel solutions to meet critical project needs. Critically reviews technical and scientific reports from external sources and coordinates Takeda-sponsored work. Education & Competencies (Technical and Behavioral): Education / Experience: BS 18 years of experience; MS 16 years of experience; PhD 10 years of experience Technical Skills/Competencies: Ability to propose and influence development to result in a commercially viable product. Must have the maturity to utilize scientific and technical knowledge to provide unique business solutions. Experience must be in a scientific discipline with expert knowledge of pharmaceutical development, including an understanding of current laboratory techniques, instrumentation, problem solving techniques, process engineering and manufacturing development, and statistics used in experimental work. Regularly contributes functional expertise to external industry and advocacy groups. Must demonstrate knowledge of several allied fields, such as chemical engineering, analytical/organic/physical chemistry, process engineering, pharmaceutics, quality assurance and/or regulatory affairs. Advanced understanding in DMPK, Pharmacology and Toxicology. Extensive knowledge of current Good Manufacturing Practices (cGMP), ICH Guidelines, other pertinent national regulations, compendial requirements and communicating with regulatory agencies. Must have experience in global regulatory submission requirements and processes. Program Leadership Skills/Competencies: Experience with the application of project leadership knowledge, skills, tools, and techniques for complex multidisciplinary programs and initiatives. Leadership - develops and uses knowledge and interpersonal skills to influence and guide internal and external stakeholders towards the accomplishment of program, divisional and corporate goals and objectives; adapts well to different personalities and manages others on the team in a respectful manner. Risk Management - ability to identify/solve technical, budgetary, and schedule risks to multiple programs and propose appropriate risk response strategies. Ability to identify gaps in CMC technology/trends and influence change/improvements to affected areas/processes. Communication - ability to expresses one’s self clearly and concisely to key stakeholders; documents issues and/or concerns concisely and comprehensively; adjusts style, language and/or terminology appropriate for the audience. Can represent CMC viewpoint at corporate and industry level. Resource Management - ability to anticipate and manage internal and external resource needs (people, information, technologies, time, and capital). Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $177,000.00 - $278,080.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Senior Program Manager, Pharmaceutical Sciences (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Objective / Purpose: Expected to engage others by inspiring commitment. Collaborate by influencing through relationships, mobilize high performance, anticipate the group’s future needs and help develop capabilities aligned with those needs. Champion change and be a role model for junior staff not only in technical expertise but across Takeda competencies. Independently leads development of strategy and plans for multiple, complex programs Regularly leads and influences functional/divisional strategy, operations and innovation Functional thought leader and mentor Impactful contributor to divisional initiatives and may contribute to corporate, cross-divisional, and global initiatives Accountabilities: Program Leadership : Provides strategic scientific leadership and program management for multiple global CMC development teams dealing with complex development programs that require scientific depth and overall product development acumen for successful execution Identifies, mitigates and communicates project or program risks to relevant stakeholders. This person is expected to advance not only the program teams they lead but also other teams that are facing unique challenges. Lead/participates as functional expert in divisional and cross-divisional initiatives. Represents CMC on cross-divisional governance and development teams while providing strategy and accountability for CMC deliverables. Technical Acumen : Provides scientific leadership and innovation in pharmaceutical research and development. Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives. Mentors other members of the department to develop their abilities to lead and advance their individual skills of pharmaceutical product development. Demonstrates humility and approachability in encouraging others to challenge ideas and openly raise issues. Acts as an internal consultant to the Pharmaceutical Sciences staff for any scientific advice that may be needed on a project basis. Develops the capabilities of the department by identifying opportunities and anticipating changes in the business landscape through an understanding and ongoing assessment of the environment affecting the business. Represents Pharmaceutical Sciences in cross divisional, corporate and global initiatives. Cultivates a broad network of relationships throughout Takeda, with affiliates and alliance partners, in the industry and area of expertise. Inspires commitment through a wide range of communication channels (meetings, writing, and presentations). Develops and communicates convincing business cases for department strategies that motivate stakeholders to take action. Ensures that technical and scientific standards within the function meet state-of-the-art industry expectations. Identifies, evaluates, develops, recommends and/or negotiates novel solutions to meet critical project needs. Critically reviews technical and scientific reports from external sources and coordinates Takeda-sponsored work. Education & Competencies (Technical and Behavioral): Education / Experience: BS 18 years of experience; MS 16 years of experience; PhD 10 years of experience Technical Skills/Competencies: Ability to propose and influence development to result in a commercially viable product. Must have the maturity to utilize scientific and technical knowledge to provide unique business solutions. Experience must be in a scientific discipline with expert knowledge of pharmaceutical development, including an understanding of current laboratory techniques, instrumentation, problem solving techniques, process engineering and manufacturing development, and statistics used in experimental work. Regularly contributes functional expertise to external industry and advocacy groups. Must demonstrate knowledge of several allied fields, such as chemical engineering, analytical/organic/physical chemistry, process engineering, pharmaceutics, quality assurance and/or regulatory affairs. Advanced understanding in DMPK, Pharmacology and Toxicology. Extensive knowledge of current Good Manufacturing Practices (cGMP), ICH Guidelines, other pertinent national regulations, compendial requirements and communicating with regulatory agencies. Must have experience in global regulatory submission requirements and processes. Program Leadership Skills/Competencies: Experience with the application of project leadership knowledge, skills, tools, and techniques for complex multidisciplinary programs and initiatives. Leadership - develops and uses knowledge and interpersonal skills to influence and guide internal and external stakeholders towards the accomplishment of program, divisional and corporate goals and objectives; adapts well to different personalities and manages others on the team in a respectful manner. Risk Management - ability to identify/solve technical, budgetary, and schedule risks to multiple programs and propose appropriate risk response strategies. Ability to identify gaps in CMC technology/trends and influence change/improvements to affected areas/processes. Communication - ability to expresses one’s self clearly and concisely to key stakeholders; documents issues and/or concerns concisely and comprehensively; adjusts style, language and/or terminology appropriate for the audience. Can represent CMC viewpoint at corporate and industry level. Resource Management - ability to anticipate and manage internal and external resource needs (people, information, technologies, time, and capital). Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $177,000.00 - $278,080.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Head of Pharmaceutical Sciences Initiatives (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Objective / Purpose: Expected to engage others by inspiring commitment. Collaborate by influencing through relationships, mobilize high performance, anticipate the group’s future needs and help develop capabilities aligned with those needs. Champion change and be a role model for junior staff not only in technical expertise but across Takeda competencies. Independently leads development of strategy and plans for multiple, complex programs Regularly leads and influences functional/divisional strategy, operations and innovation Functional thought leader and mentor Impactful contributor to divisional initiatives and may contribute to corporate, cross-divisional, and global initiatives Accountabilities: Program Leadership : Provides strategic scientific leadership and program management for multiple global CMC development teams dealing with complex development programs that require scientific depth and overall product development acumen for successful execution Identifies, mitigates and communicates project or program risks to relevant stakeholders. This person is expected to advance not only the program teams they lead but also other teams that are facing unique challenges. Lead/participates as functional expert in divisional and cross-divisional initiatives. Represents CMC on cross-divisional governance and development teams while providing strategy and accountability for CMC deliverables. Technical Acumen : Provides scientific leadership and innovation in pharmaceutical research and development. Builds teams across functions and geographies with individuals who have the right skills and experience to deliver on key organizational initiatives. Mentors other members of the department to develop their abilities to lead and advance their individual skills of pharmaceutical product development. Demonstrates humility and approachability in encouraging others to challenge ideas and openly raise issues. Acts as an internal consultant to the Pharmaceutical Sciences staff for any scientific advice that may be needed on a project basis. Develops the capabilities of the department by identifying opportunities and anticipating changes in the business landscape through an understanding and ongoing assessment of the environment affecting the business. Represents Pharmaceutical Sciences in cross divisional, corporate and global initiatives. Cultivates a broad network of relationships throughout Takeda, with affiliates and alliance partners, in the industry and area of expertise. Inspires commitment through a wide range of communication channels (meetings, writing, and presentations). Develops and communicates convincing business cases for department strategies that motivate stakeholders to take action. Ensures that technical and scientific standards within the function meet state-of-the-art industry expectations. Identifies, evaluates, develops, recommends and/or negotiates novel solutions to meet critical project needs. Critically reviews technical and scientific reports from external sources and coordinates Takeda-sponsored work. Education & Competencies (Technical and Behavioral): Education / Experience: BS 18 years of experience; MS 16 years of experience; PhD 10 years of experience Technical Skills/Competencies: Ability to propose and influence development to result in a commercially viable product. Must have the maturity to utilize scientific and technical knowledge to provide unique business solutions. Experience must be in a scientific discipline with expert knowledge of pharmaceutical development, including an understanding of current laboratory techniques, instrumentation, problem solving techniques, process engineering and manufacturing development, and statistics used in experimental work. Regularly contributes functional expertise to external industry and advocacy groups. Must demonstrate knowledge of several allied fields, such as chemical engineering, analytical/organic/physical chemistry, process engineering, pharmaceutics, quality assurance and/or regulatory affairs. Advanced understanding in DMPK, Pharmacology and Toxicology. Extensive knowledge of current Good Manufacturing Practices (cGMP), ICH Guidelines, other pertinent national regulations, compendial requirements and communicating with regulatory agencies. Must have experience in global regulatory submission requirements and processes. Program Leadership Skills/Competencies: Experience with the application of project leadership knowledge, skills, tools, and techniques for complex multidisciplinary programs and initiatives. Leadership - develops and uses knowledge and interpersonal skills to influence and guide internal and external stakeholders towards the accomplishment of program, divisional and corporate goals and objectives; adapts well to different personalities and manages others on the team in a respectful manner. Risk Management - ability to identify/solve technical, budgetary, and schedule risks to multiple programs and propose appropriate risk response strategies. Ability to identify gaps in CMC technology/trends and influence change/improvements to affected areas/processes. Communication - ability to expresses one’s self clearly and concisely to key stakeholders; documents issues and/or concerns concisely and comprehensively; adjusts style, language and/or terminology appropriate for the audience. Can represent CMC viewpoint at corporate and industry level. Resource Management - ability to anticipate and manage internal and external resource needs (people, information, technologies, time, and capital). Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $177,000.00 - $278,080.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Executive Director, Global Program Lead (CAMBRIDGE)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Executive Director, Global Program Leader (GPL) in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Takeda seeks an experienced and highly skilled drug development leader to lead the program team for an innovative hepatology program, which is evaluating a first-in-class molecule intended for a rare disease. The current program encompasses multiple ongoing clinical trials, including a phase 3 registrational study. The individual appointed to this role will be accountable for advancing the program through regulatory filing, approval, and eventual commercialization. The Global Program Leader is a seasoned drug development leader fully dedicated, responsible and accountable for overarching Global Program(s). The GPL defines the asset strategy and leads all development and Life Cycle Management projects associated with an asset from discovery to the marketplace. The guiding framework for this role is defined by Takedas’ values of Patient-Trust-Reputation-Business. In addition to project specific responsibilities, the ED GPL may be called upon to represent the GPL community in enterprise-wide initiatives to improve speed/cost to market (e.g. innovative trial designs, improving governance processes, asset strategy etc.) GPLs must be experienced, versatile and strong enterprise leaders be committed to simultaneously driving programs to regulatory approval as well as product launch and global patient access have the ability to partner with all functions to drive, deliver and maximize asset value. be recognized as an outstanding cross-functional leader with a track-record of consistently delivering against challenging goals communicate effectively, be adept at taking decisions as well as facilitating joint decision making This is best achieved by a unique fit for purpose combination of the competencies listed below. Inspirational Leadership Strategic Vision Strong Analytical Credibility Execution Skills Stakeholder Relationship Management For a given asset, responsible for an overarching global program strategy and execution. The GPL leads all research, development, commercial and LCM activities associated with an asset from discovery to the marketplace with full accountability. Leads the Asset Strategy together with the commercial leader in the context of unmet medical need, competitive landscape, and key TPP attributes required to bring the product to market and to ensure global access for patients in context of Takeda’s values: Patient-Trust-Reputation-Business. This must take into consideration all development and commercial requirements as well as potential local/regional key requirements For a given asset, the GPL is the single leader of a cross functional team, the Global Program Team (GPT). The GPL ensures, through the functional sub-teams leaders and their teams, that all project deliverables achieve defined project scope & objectives, budget and timelines with full functional support, keeping in mind value maximization and strong sense of the time/quality balance. Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables of the functional sub-teams for a given asset. GPT members are directly accountable to the GPL on the sub-team objectives. Accountable with the Global Program Manager for operating budgets within the global program; leads budget setting in collaboration with functions and manages variance to budget ensuring overall Takeda financial objectives are met. Reports on program progress, issues, related updates, new requests for decision related to strategic scope or budget increase (new recommendations, change or buy-up) or timelines change and risks to TA Unit Head and/or the Takeda executive management governance committees per company process. Manages several assets of increasing complexity (including newer platform technologies), depending on the size and stage or the programs Showcases the GPL leadership skills and Enterprise GPT operating model functioning and deliverables through all job attributes defined at Takeda May lead key business initiatives: including evaluating new opportunities and providing overall support for feasibility studies on potential global programs. May represent GPL community in internal development optimization initiatives such as refresh to asset strategy, innovative trial design etc. Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively to the GPL community ACCOUNTABILITIES: Program Strategy, Activity Planning and Execution Oversees and leads all program team interactions with FDA and other regulatory authorities and key opinion leaders relevant to assigned compounds. Proactive identification of challenges and development of contingency plans as appropriate. Leads the Global Program Team in setting program vision, strategy, goals, priorities and long-term plans and schedules. Aligns cross-functional, cross-divisional project goals with Takeda business needs and strategies. Works closely with the GPM in order to provide strategic, process, and operational leadership to multiple GPTs and Takeda functions in the successful delivery of projects from discovery to commercialization and LCM activities. Could manage 3-5 projects across all phases of development including innovative early POM/POC in novel mechanisms with less-defined regulatory pathways through large-scale Phase III/submission projects and global launch projects. Links GPT cross-functional sub-teams, such as the Clinical Subteam, Commercial Subteam, Pharmaceutical Sciences (CMC) Subteam, etc. to the GPT through function-based subteam leaders to execute according to the Enterprise GPT Playbook, align and ensure transparency of all program-related activities. Provides leadership and support to TA Leaders and Sub-team leaders to set the vision and direction for the Therapeutic Area and prioritizes all aspects of projects within a global program. Reports on progress of projects, plans/plan changes, critical path, possible scenario and issues/risks/impact to TA Unit and Takeda executive management through internal or external reviews of global programs. Leads key business initiatives: for example, evaluates new opportunities (i.e.: in-licensing candidates, impact of change in market conditions or availability of new project data in disease areas where Takeda has little or no previous experience) and provides overall support for feasibility studies on potential global programs-non exhaustive list Fiscal Responsibility Accountable with the responsible GPM for project operating budgets within the global program; monitors and controls expenditures; manages variance between budgeted and actual expenditures of time, dollars, and personnel while meeting overall Takeda financial objectives. Resource and Issue Management Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment. Manages internal and external resources (people, information, technologies, time, and capital); allocates project resources appropriately, given division, function and individual goals and objectives to align with business imperatives. Proactively and regularly identifies/monitor project risks before they transform into issues and develops contingency plans; communicates timely and proactively project-related issues to senior executive management and manages issues to resolution. Consults with TAU, Franchise Leadership and Portfolio Office to deliver accurate and timely project status and deliverable information to enable the organization to focus on key priorities and enhance its ability to deliver work (e.g., studies/projects) on-time and on-budget (including proficient use of systems to improve reporting or acces

Executive Director, Global Program Lead - Innovation-focused Leadership (CAMBRIDGE)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Executive Director, Global Program Leader (GPL) in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Takeda seeks an experienced and highly skilled drug development leader to lead the program team for an innovative hepatology program, which is evaluating a first-in-class molecule intended for a rare disease. The current program encompasses multiple ongoing clinical trials, including a phase 3 registrational study. The individual appointed to this role will be accountable for advancing the program through regulatory filing, approval, and eventual commercialization. The Global Program Leader is a seasoned drug development leader fully dedicated, responsible and accountable for overarching Global Program(s). The GPL defines the asset strategy and leads all development and Life Cycle Management projects associated with an asset from discovery to the marketplace. The guiding framework for this role is defined by Takedas’ values of Patient-Trust-Reputation-Business. In addition to project specific responsibilities, the ED GPL may be called upon to represent the GPL community in enterprise-wide initiatives to improve speed/cost to market (e.g. innovative trial designs, improving governance processes, asset strategy etc.) GPLs must be experienced, versatile and strong enterprise leaders be committed to simultaneously driving programs to regulatory approval as well as product launch and global patient access have the ability to partner with all functions to drive, deliver and maximize asset value. be recognized as an outstanding cross-functional leader with a track-record of consistently delivering against challenging goals communicate effectively, be adept at taking decisions as well as facilitating joint decision making This is best achieved by a unique fit for purpose combination of the competencies listed below. Inspirational Leadership Strategic Vision Strong Analytical Credibility Execution Skills Stakeholder Relationship Management For a given asset, responsible for an overarching global program strategy and execution. The GPL leads all research, development, commercial and LCM activities associated with an asset from discovery to the marketplace with full accountability. Leads the Asset Strategy together with the commercial leader in the context of unmet medical need, competitive landscape, and key TPP attributes required to bring the product to market and to ensure global access for patients in context of Takeda’s values: Patient-Trust-Reputation-Business. This must take into consideration all development and commercial requirements as well as potential local/regional key requirements For a given asset, the GPL is the single leader of a cross functional team, the Global Program Team (GPT). The GPL ensures, through the functional sub-teams leaders and their teams, that all project deliverables achieve defined project scope & objectives, budget and timelines with full functional support, keeping in mind value maximization and strong sense of the time/quality balance. Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables of the functional sub-teams for a given asset. GPT members are directly accountable to the GPL on the sub-team objectives. Accountable with the Global Program Manager for operating budgets within the global program; leads budget setting in collaboration with functions and manages variance to budget ensuring overall Takeda financial objectives are met. Reports on program progress, issues, related updates, new requests for decision related to strategic scope or budget increase (new recommendations, change or buy-up) or timelines change and risks to TA Unit Head and/or the Takeda executive management governance committees per company process. Manages several assets of increasing complexity (including newer platform technologies), depending on the size and stage or the programs Showcases the GPL leadership skills and Enterprise GPT operating model functioning and deliverables through all job attributes defined at Takeda May lead key business initiatives: including evaluating new opportunities and providing overall support for feasibility studies on potential global programs. May represent GPL community in internal development optimization initiatives such as refresh to asset strategy, innovative trial design etc. Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively to the GPL community ACCOUNTABILITIES: Program Strategy, Activity Planning and Execution Oversees and leads all program team interactions with FDA and other regulatory authorities and key opinion leaders relevant to assigned compounds. Proactive identification of challenges and development of contingency plans as appropriate. Leads the Global Program Team in setting program vision, strategy, goals, priorities and long-term plans and schedules. Aligns cross-functional, cross-divisional project goals with Takeda business needs and strategies. Works closely with the GPM in order to provide strategic, process, and operational leadership to multiple GPTs and Takeda functions in the successful delivery of projects from discovery to commercialization and LCM activities. Could manage 3-5 projects across all phases of development including innovative early POM/POC in novel mechanisms with less-defined regulatory pathways through large-scale Phase III/submission projects and global launch projects. Links GPT cross-functional sub-teams, such as the Clinical Subteam, Commercial Subteam, Pharmaceutical Sciences (CMC) Subteam, etc. to the GPT through function-based subteam leaders to execute according to the Enterprise GPT Playbook, align and ensure transparency of all program-related activities. Provides leadership and support to TA Leaders and Sub-team leaders to set the vision and direction for the Therapeutic Area and prioritizes all aspects of projects within a global program. Reports on progress of projects, plans/plan changes, critical path, possible scenario and issues/risks/impact to TA Unit and Takeda executive management through internal or external reviews of global programs. Leads key business initiatives: for example, evaluates new opportunities (i.e.: in-licensing candidates, impact of change in market conditions or availability of new project data in disease areas where Takeda has little or no previous experience) and provides overall support for feasibility studies on potential global programs-non exhaustive list Fiscal Responsibility Accountable with the responsible GPM for project operating budgets within the global program; monitors and controls expenditures; manages variance between budgeted and actual expenditures of time, dollars, and personnel while meeting overall Takeda financial objectives. Resource and Issue Management Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment. Manages internal and external resources (people, information, technologies, time, and capital); allocates project resources appropriately, given division, function and individual goals and objectives to align with business imperatives. Proactively and regularly identifies/monitor project risks before they transform into issues and develops contingency plans; communicates timely and proactively project-related issues to senior executive management and manages issues to resolution. Consults with TAU, Franchise Leadership and Portfolio Office to deliver accurate and timely project status and deliverable information to enable the organization to focus on key priorities and enhance its ability to deliver work (e.g., studies/projects) on-time and on-budget (including proficient use of systems to improve reporting or acces

Senior Vice President, International Program Management (CAMBRIDGE)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Executive Director, Global Program Leader (GPL) in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Takeda seeks an experienced and highly skilled drug development leader to lead the program team for an innovative hepatology program, which is evaluating a first-in-class molecule intended for a rare disease. The current program encompasses multiple ongoing clinical trials, including a phase 3 registrational study. The individual appointed to this role will be accountable for advancing the program through regulatory filing, approval, and eventual commercialization. The Global Program Leader is a seasoned drug development leader fully dedicated, responsible and accountable for overarching Global Program(s). The GPL defines the asset strategy and leads all development and Life Cycle Management projects associated with an asset from discovery to the marketplace. The guiding framework for this role is defined by Takedas’ values of Patient-Trust-Reputation-Business. In addition to project specific responsibilities, the ED GPL may be called upon to represent the GPL community in enterprise-wide initiatives to improve speed/cost to market (e.g. innovative trial designs, improving governance processes, asset strategy etc.) GPLs must be experienced, versatile and strong enterprise leaders be committed to simultaneously driving programs to regulatory approval as well as product launch and global patient access have the ability to partner with all functions to drive, deliver and maximize asset value. be recognized as an outstanding cross-functional leader with a track-record of consistently delivering against challenging goals communicate effectively, be adept at taking decisions as well as facilitating joint decision making This is best achieved by a unique fit for purpose combination of the competencies listed below. Inspirational Leadership Strategic Vision Strong Analytical Credibility Execution Skills Stakeholder Relationship Management For a given asset, responsible for an overarching global program strategy and execution. The GPL leads all research, development, commercial and LCM activities associated with an asset from discovery to the marketplace with full accountability. Leads the Asset Strategy together with the commercial leader in the context of unmet medical need, competitive landscape, and key TPP attributes required to bring the product to market and to ensure global access for patients in context of Takeda’s values: Patient-Trust-Reputation-Business. This must take into consideration all development and commercial requirements as well as potential local/regional key requirements For a given asset, the GPL is the single leader of a cross functional team, the Global Program Team (GPT). The GPL ensures, through the functional sub-teams leaders and their teams, that all project deliverables achieve defined project scope & objectives, budget and timelines with full functional support, keeping in mind value maximization and strong sense of the time/quality balance. Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables of the functional sub-teams for a given asset. GPT members are directly accountable to the GPL on the sub-team objectives. Accountable with the Global Program Manager for operating budgets within the global program; leads budget setting in collaboration with functions and manages variance to budget ensuring overall Takeda financial objectives are met. Reports on program progress, issues, related updates, new requests for decision related to strategic scope or budget increase (new recommendations, change or buy-up) or timelines change and risks to TA Unit Head and/or the Takeda executive management governance committees per company process. Manages several assets of increasing complexity (including newer platform technologies), depending on the size and stage or the programs Showcases the GPL leadership skills and Enterprise GPT operating model functioning and deliverables through all job attributes defined at Takeda May lead key business initiatives: including evaluating new opportunities and providing overall support for feasibility studies on potential global programs. May represent GPL community in internal development optimization initiatives such as refresh to asset strategy, innovative trial design etc. Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively to the GPL community ACCOUNTABILITIES: Program Strategy, Activity Planning and Execution Oversees and leads all program team interactions with FDA and other regulatory authorities and key opinion leaders relevant to assigned compounds. Proactive identification of challenges and development of contingency plans as appropriate. Leads the Global Program Team in setting program vision, strategy, goals, priorities and long-term plans and schedules. Aligns cross-functional, cross-divisional project goals with Takeda business needs and strategies. Works closely with the GPM in order to provide strategic, process, and operational leadership to multiple GPTs and Takeda functions in the successful delivery of projects from discovery to commercialization and LCM activities. Could manage 3-5 projects across all phases of development including innovative early POM/POC in novel mechanisms with less-defined regulatory pathways through large-scale Phase III/submission projects and global launch projects. Links GPT cross-functional sub-teams, such as the Clinical Subteam, Commercial Subteam, Pharmaceutical Sciences (CMC) Subteam, etc. to the GPT through function-based subteam leaders to execute according to the Enterprise GPT Playbook, align and ensure transparency of all program-related activities. Provides leadership and support to TA Leaders and Sub-team leaders to set the vision and direction for the Therapeutic Area and prioritizes all aspects of projects within a global program. Reports on progress of projects, plans/plan changes, critical path, possible scenario and issues/risks/impact to TA Unit and Takeda executive management through internal or external reviews of global programs. Leads key business initiatives: for example, evaluates new opportunities (i.e.: in-licensing candidates, impact of change in market conditions or availability of new project data in disease areas where Takeda has little or no previous experience) and provides overall support for feasibility studies on potential global programs-non exhaustive list Fiscal Responsibility Accountable with the responsible GPM for project operating budgets within the global program; monitors and controls expenditures; manages variance between budgeted and actual expenditures of time, dollars, and personnel while meeting overall Takeda financial objectives. Resource and Issue Management Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment. Manages internal and external resources (people, information, technologies, time, and capital); allocates project resources appropriately, given division, function and individual goals and objectives to align with business imperatives. Proactively and regularly identifies/monitor project risks before they transform into issues and develops contingency plans; communicates timely and proactively project-related issues to senior executive management and manages issues to resolution. Consults with TAU, Franchise Leadership and Portfolio Office to deliver accurate and timely project status and deliverable information to enable the organization to focus on key priorities and enhance its ability to deliver work (e.g., studies/projects) on-time and on-budget (including proficient use of systems to improve reporting or acces

Chief Global Operations Officer (CAMBRIDGE)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as an Executive Director, Global Program Leader (GPL) in our Cambridge office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. OBJECTIVES: Takeda seeks an experienced and highly skilled drug development leader to lead the program team for an innovative hepatology program, which is evaluating a first-in-class molecule intended for a rare disease. The current program encompasses multiple ongoing clinical trials, including a phase 3 registrational study. The individual appointed to this role will be accountable for advancing the program through regulatory filing, approval, and eventual commercialization. The Global Program Leader is a seasoned drug development leader fully dedicated, responsible and accountable for overarching Global Program(s). The GPL defines the asset strategy and leads all development and Life Cycle Management projects associated with an asset from discovery to the marketplace. The guiding framework for this role is defined by Takedas’ values of Patient-Trust-Reputation-Business. In addition to project specific responsibilities, the ED GPL may be called upon to represent the GPL community in enterprise-wide initiatives to improve speed/cost to market (e.g. innovative trial designs, improving governance processes, asset strategy etc.) GPLs must be experienced, versatile and strong enterprise leaders be committed to simultaneously driving programs to regulatory approval as well as product launch and global patient access have the ability to partner with all functions to drive, deliver and maximize asset value. be recognized as an outstanding cross-functional leader with a track-record of consistently delivering against challenging goals communicate effectively, be adept at taking decisions as well as facilitating joint decision making This is best achieved by a unique fit for purpose combination of the competencies listed below. Inspirational Leadership Strategic Vision Strong Analytical Credibility Execution Skills Stakeholder Relationship Management For a given asset, responsible for an overarching global program strategy and execution. The GPL leads all research, development, commercial and LCM activities associated with an asset from discovery to the marketplace with full accountability. Leads the Asset Strategy together with the commercial leader in the context of unmet medical need, competitive landscape, and key TPP attributes required to bring the product to market and to ensure global access for patients in context of Takeda’s values: Patient-Trust-Reputation-Business. This must take into consideration all development and commercial requirements as well as potential local/regional key requirements For a given asset, the GPL is the single leader of a cross functional team, the Global Program Team (GPT). The GPL ensures, through the functional sub-teams leaders and their teams, that all project deliverables achieve defined project scope & objectives, budget and timelines with full functional support, keeping in mind value maximization and strong sense of the time/quality balance. Provides matrix management, strategic and tactical leadership to GPT members who are responsible for leading the key deliverables of the functional sub-teams for a given asset. GPT members are directly accountable to the GPL on the sub-team objectives. Accountable with the Global Program Manager for operating budgets within the global program; leads budget setting in collaboration with functions and manages variance to budget ensuring overall Takeda financial objectives are met. Reports on program progress, issues, related updates, new requests for decision related to strategic scope or budget increase (new recommendations, change or buy-up) or timelines change and risks to TA Unit Head and/or the Takeda executive management governance committees per company process. Manages several assets of increasing complexity (including newer platform technologies), depending on the size and stage or the programs Showcases the GPL leadership skills and Enterprise GPT operating model functioning and deliverables through all job attributes defined at Takeda May lead key business initiatives: including evaluating new opportunities and providing overall support for feasibility studies on potential global programs. May represent GPL community in internal development optimization initiatives such as refresh to asset strategy, innovative trial design etc. Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively to the GPL community ACCOUNTABILITIES: Program Strategy, Activity Planning and Execution Oversees and leads all program team interactions with FDA and other regulatory authorities and key opinion leaders relevant to assigned compounds. Proactive identification of challenges and development of contingency plans as appropriate. Leads the Global Program Team in setting program vision, strategy, goals, priorities and long-term plans and schedules. Aligns cross-functional, cross-divisional project goals with Takeda business needs and strategies. Works closely with the GPM in order to provide strategic, process, and operational leadership to multiple GPTs and Takeda functions in the successful delivery of projects from discovery to commercialization and LCM activities. Could manage 3-5 projects across all phases of development including innovative early POM/POC in novel mechanisms with less-defined regulatory pathways through large-scale Phase III/submission projects and global launch projects. Links GPT cross-functional sub-teams, such as the Clinical Subteam, Commercial Subteam, Pharmaceutical Sciences (CMC) Subteam, etc. to the GPT through function-based subteam leaders to execute according to the Enterprise GPT Playbook, align and ensure transparency of all program-related activities. Provides leadership and support to TA Leaders and Sub-team leaders to set the vision and direction for the Therapeutic Area and prioritizes all aspects of projects within a global program. Reports on progress of projects, plans/plan changes, critical path, possible scenario and issues/risks/impact to TA Unit and Takeda executive management through internal or external reviews of global programs. Leads key business initiatives: for example, evaluates new opportunities (i.e.: in-licensing candidates, impact of change in market conditions or availability of new project data in disease areas where Takeda has little or no previous experience) and provides overall support for feasibility studies on potential global programs-non exhaustive list Fiscal Responsibility Accountable with the responsible GPM for project operating budgets within the global program; monitors and controls expenditures; manages variance between budgeted and actual expenditures of time, dollars, and personnel while meeting overall Takeda financial objectives. Resource and Issue Management Responsible for evaluation of external interactions in the context of overall development strategies using complex problem solving in the region but in context of a global environment. Manages internal and external resources (people, information, technologies, time, and capital); allocates project resources appropriately, given division, function and individual goals and objectives to align with business imperatives. Proactively and regularly identifies/monitor project risks before they transform into issues and develops contingency plans; communicates timely and proactively project-related issues to senior executive management and manages issues to resolution. Consults with TAU, Franchise Leadership and Portfolio Office to deliver accurate and timely project status and deliverable information to enable the organization to focus on key priorities and enhance its ability to deliver work (e.g., studies/projects) on-time and on-budget (including proficient use of systems to improve reporting or acces

Head of R&D Global Capability Centers (Vice President) (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: The Head of R&D Global Capability Centers (GCC) is a senior enterprise leadership role accountable for shaping, establishing, and scaling Takeda’s globally integrated, multi-hub R&D delivery model. The role serves as the single, cross‑R&D point of accountability for GCC strategy, operating model design, and execution, and acts as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership Team during hub establishment and early maturity phases. Operating at an executive level, this leader partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs in Poland and India are established and fully integrated into Takeda R&D, delivering sustainable capabilities, talent pipelines, and long‑term enterprise value. How you will contribute: Takeda is seeking a senior R&D leader to own R&D’s Global Capability Center (GCC) vision, and lead and coordinate R&D GCC activities across the enterprise. This role is accountable for coordinating the establishment and scaling of R&D hub locations in Poland and India, aligned to a multi-hub, globally integrated R&D development model. The role operates as the single, cross‑R&D point of accountability for GCC strategy, execution, and integration, and serves as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership during hub stand‑up and early maturity phases. This position reports into the Head of R&D Operational Excellence and partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs deliver both near‑term value and long‑term capability building. This role requires significant cross functional leadership. Strategic Context: This role supports Takeda’s evolution toward a globally integrated, multi‑hub R&D model that: Establishes Cambridge, MA, Poland, and Bangaluru, India as interconnected R&D hubs Focus on capability and talent development Enables hybrid Global Program Team (GPT) execution across hubs Requires strong central leadership to coordinate governance, integration, and change management Key Responsibilities: Enterprise & R&D Leadership: Serve as the R&D‑wide GCC Lead with accountability for strategy, execution, and evolution Act as primary R&D counterpart to the Enterprise Transformation Office and R&D Leadership Representing GCC strategy with senior R&D and enterprise governance forums GCC Strategy & Operating Model: Define the multi‑year GCC vision and roadmap Design and implement the multi‑hub operating model Ensure alignment with R&D functional strategies Hub Establishment & Scale‑Up (Poland & India): Lead R&D input into hub stand‑up Partner with enterprise teams on infrastructure, talent, and change Enable phased capability scaling Cross‑Functional Coordination: Coordinate across R&D functions and Therapeutic Areas Resolve cross‑functional dependencies Ensure clear accountability Talent, Capability & Culture: Shape leadership and talent models Support sustainable talent pipelines Promote Takeda values Minimum Requirements/Qualifications: Required: 15 years leadership experience in life sciences R&D Experience across multiple R&D functions Large‑scale transformation leadership Global Capability Center operating experience Preferred: GCC or global delivery hub experience Hybrid operating model exposure Digital, data, or AI‑enabled R&D transformation Advanced degree Travel: 30% travel required This position is currently classified as hybrid in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $259,000.00 - $407,000.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Head of R&D Global Capability Centers (Vice President) - Transformational R&D Leadership (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: The Head of R&D Global Capability Centers (GCC) is a senior enterprise leadership role accountable for shaping, establishing, and scaling Takeda’s globally integrated, multi-hub R&D delivery model. The role serves as the single, cross‑R&D point of accountability for GCC strategy, operating model design, and execution, and acts as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership Team during hub establishment and early maturity phases. Operating at an executive level, this leader partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs in Poland and India are established and fully integrated into Takeda R&D, delivering sustainable capabilities, talent pipelines, and long‑term enterprise value. How you will contribute: Takeda is seeking a senior R&D leader to own R&D’s Global Capability Center (GCC) vision, and lead and coordinate R&D GCC activities across the enterprise. This role is accountable for coordinating the establishment and scaling of R&D hub locations in Poland and India, aligned to a multi-hub, globally integrated R&D development model. The role operates as the single, cross‑R&D point of accountability for GCC strategy, execution, and integration, and serves as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership during hub stand‑up and early maturity phases. This position reports into the Head of R&D Operational Excellence and partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs deliver both near‑term value and long‑term capability building. This role requires significant cross functional leadership. Strategic Context: This role supports Takeda’s evolution toward a globally integrated, multi‑hub R&D model that: Establishes Cambridge, MA, Poland, and Bangaluru, India as interconnected R&D hubs Focus on capability and talent development Enables hybrid Global Program Team (GPT) execution across hubs Requires strong central leadership to coordinate governance, integration, and change management Key Responsibilities: Enterprise & R&D Leadership: Serve as the R&D‑wide GCC Lead with accountability for strategy, execution, and evolution Act as primary R&D counterpart to the Enterprise Transformation Office and R&D Leadership Representing GCC strategy with senior R&D and enterprise governance forums GCC Strategy & Operating Model: Define the multi‑year GCC vision and roadmap Design and implement the multi‑hub operating model Ensure alignment with R&D functional strategies Hub Establishment & Scale‑Up (Poland & India): Lead R&D input into hub stand‑up Partner with enterprise teams on infrastructure, talent, and change Enable phased capability scaling Cross‑Functional Coordination: Coordinate across R&D functions and Therapeutic Areas Resolve cross‑functional dependencies Ensure clear accountability Talent, Capability & Culture: Shape leadership and talent models Support sustainable talent pipelines Promote Takeda values Minimum Requirements/Qualifications: Required: 15 years leadership experience in life sciences R&D Experience across multiple R&D functions Large‑scale transformation leadership Global Capability Center operating experience Preferred: GCC or global delivery hub experience Hybrid operating model exposure Digital, data, or AI‑enabled R&D transformation Advanced degree Travel: 30% travel required This position is currently classified as hybrid in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $259,000.00 - $407,000.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Chief of Global R&D Strategy (Vice President) (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: The Head of R&D Global Capability Centers (GCC) is a senior enterprise leadership role accountable for shaping, establishing, and scaling Takeda’s globally integrated, multi-hub R&D delivery model. The role serves as the single, cross‑R&D point of accountability for GCC strategy, operating model design, and execution, and acts as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership Team during hub establishment and early maturity phases. Operating at an executive level, this leader partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs in Poland and India are established and fully integrated into Takeda R&D, delivering sustainable capabilities, talent pipelines, and long‑term enterprise value. How you will contribute: Takeda is seeking a senior R&D leader to own R&D’s Global Capability Center (GCC) vision, and lead and coordinate R&D GCC activities across the enterprise. This role is accountable for coordinating the establishment and scaling of R&D hub locations in Poland and India, aligned to a multi-hub, globally integrated R&D development model. The role operates as the single, cross‑R&D point of accountability for GCC strategy, execution, and integration, and serves as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership during hub stand‑up and early maturity phases. This position reports into the Head of R&D Operational Excellence and partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs deliver both near‑term value and long‑term capability building. This role requires significant cross functional leadership. Strategic Context: This role supports Takeda’s evolution toward a globally integrated, multi‑hub R&D model that: Establishes Cambridge, MA, Poland, and Bangaluru, India as interconnected R&D hubs Focus on capability and talent development Enables hybrid Global Program Team (GPT) execution across hubs Requires strong central leadership to coordinate governance, integration, and change management Key Responsibilities: Enterprise & R&D Leadership: Serve as the R&D‑wide GCC Lead with accountability for strategy, execution, and evolution Act as primary R&D counterpart to the Enterprise Transformation Office and R&D Leadership Representing GCC strategy with senior R&D and enterprise governance forums GCC Strategy & Operating Model: Define the multi‑year GCC vision and roadmap Design and implement the multi‑hub operating model Ensure alignment with R&D functional strategies Hub Establishment & Scale‑Up (Poland & India): Lead R&D input into hub stand‑up Partner with enterprise teams on infrastructure, talent, and change Enable phased capability scaling Cross‑Functional Coordination: Coordinate across R&D functions and Therapeutic Areas Resolve cross‑functional dependencies Ensure clear accountability Talent, Capability & Culture: Shape leadership and talent models Support sustainable talent pipelines Promote Takeda values Minimum Requirements/Qualifications: Required: 15 years leadership experience in life sciences R&D Experience across multiple R&D functions Large‑scale transformation leadership Global Capability Center operating experience Preferred: GCC or global delivery hub experience Hybrid operating model exposure Digital, data, or AI‑enabled R&D transformation Advanced degree Travel: 30% travel required This position is currently classified as hybrid in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $259,000.00 - $407,000.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Vice President of Global R&D Operations (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description About the role: The Head of R&D Global Capability Centers (GCC) is a senior enterprise leadership role accountable for shaping, establishing, and scaling Takeda’s globally integrated, multi-hub R&D delivery model. The role serves as the single, cross‑R&D point of accountability for GCC strategy, operating model design, and execution, and acts as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership Team during hub establishment and early maturity phases. Operating at an executive level, this leader partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs in Poland and India are established and fully integrated into Takeda R&D, delivering sustainable capabilities, talent pipelines, and long‑term enterprise value. How you will contribute: Takeda is seeking a senior R&D leader to own R&D’s Global Capability Center (GCC) vision, and lead and coordinate R&D GCC activities across the enterprise. This role is accountable for coordinating the establishment and scaling of R&D hub locations in Poland and India, aligned to a multi-hub, globally integrated R&D development model. The role operates as the single, cross‑R&D point of accountability for GCC strategy, execution, and integration, and serves as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership during hub stand‑up and early maturity phases. This position reports into the Head of R&D Operational Excellence and partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs deliver both near‑term value and long‑term capability building. This role requires significant cross functional leadership. Strategic Context: This role supports Takeda’s evolution toward a globally integrated, multi‑hub R&D model that: Establishes Cambridge, MA, Poland, and Bangaluru, India as interconnected R&D hubs Focus on capability and talent development Enables hybrid Global Program Team (GPT) execution across hubs Requires strong central leadership to coordinate governance, integration, and change management Key Responsibilities: Enterprise & R&D Leadership: Serve as the R&D‑wide GCC Lead with accountability for strategy, execution, and evolution Act as primary R&D counterpart to the Enterprise Transformation Office and R&D Leadership Representing GCC strategy with senior R&D and enterprise governance forums GCC Strategy & Operating Model: Define the multi‑year GCC vision and roadmap Design and implement the multi‑hub operating model Ensure alignment with R&D functional strategies Hub Establishment & Scale‑Up (Poland & India): Lead R&D input into hub stand‑up Partner with enterprise teams on infrastructure, talent, and change Enable phased capability scaling Cross‑Functional Coordination: Coordinate across R&D functions and Therapeutic Areas Resolve cross‑functional dependencies Ensure clear accountability Talent, Capability & Culture: Shape leadership and talent models Support sustainable talent pipelines Promote Takeda values Minimum Requirements/Qualifications: Required: 15 years leadership experience in life sciences R&D Experience across multiple R&D functions Large‑scale transformation leadership Global Capability Center operating experience Preferred: GCC or global delivery hub experience Hybrid operating model exposure Digital, data, or AI‑enabled R&D transformation Advanced degree Travel: 30% travel required This position is currently classified as hybrid in accordance with Takeda's Hybrid and Remote Work policy. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Boston, MA U.S. Base Salary Range: $259,000.00 - $407,000.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Boston, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Human Factors Engineering - Associate Engineering Fellow (LEXINGTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Objective Human Factors Engineering (HFE) Lead - Associate Engineering Fellow (AEF) is responsible for Human Centered Design of Medical Devices and Combination Products. The HFE Lead - AEF will be integral to design and development of product user interface including hardware, software, packaging, labeling, and instruction material to support safe and effective use of the product for the intended use by the intended users in the anticipated use environment. The HFE Lead responsibilities include but are not limited to: Leading and executing Human Factors strategy in compliance with regional regulatory guidance. Driving and overseeing User Research strategy in compliance with Quality Management System. Developing Human Factors Product and System level requirements in alignment with Target Product Profile. Conducting exploratory research to gather user insights and design trends and evaluate user interface concepts. Translating user needs into user experience and interface requirements and specifications. Designing and executing Human Factors studies to iteratively evaluating product user interface – including hardware, software, packaging, instructional material, and training. Conducting Task and Known Use Problem Analyses. Performing use-safety engineering through Use-related Risk Analysis. Developing Human Factors Validation Protocols and Reports. Managing Human Factors, Industrial Design, and User Research vendors. Supporting regulatory Human Factors Information Requests. Developing Human Factors Summary Reports in compliance with FDA guidance. Developing Usability Engineering Files in compliance with IEC and ISO standards. Leading development to Human Factors standard operating procedures and templates development. Applying functional knowledge of applicable guidance, regulations, standards, and industry best practices to medical device and combination product design and development process. Preparing documentation to support medical device and combination product development activities including design controls. Collaborating with cross functional team members from mechanical, software, clinical, regulatory, and quality engineering disciplines. Qualifying and managing Human Factors vendors. Supporting internal and external quality audits. Communicating with internal and external key stakeholders. Mentoring Human Factors Engineering Leads. Education & Qualifications Doctorate degree and 10 years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry. OR, Master's degree and 13 years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry. OR, Bachelor's degree and 15 years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry Physical Health Requirements While the role of a Human Factors Engineering Lead primarily involves cognitive and analytical tasks, good physical health is essential. Engineers may need to visit manufacturing sites or conduct user testing in clinical environments, which might involve walking, standing, or other physical activities. Depending on the role and specific responsibilities, a Human Factors Engineering Lead may need to travel to clinical sites, supplier facilities, or other locations for research and testing purposes. Travel Requirements This position may require up to 20% yearly travel, including domestic and international. Takeda Compensation and Benefits Summary We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices. For Location: Lexington, MA U.S. Base Salary Range: $154,400.00 - $242,550.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location. U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation. EEO Statement Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law. Locations Lexington, MA Worker Type Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.