Director/Senior Director, Drug Product (, MA, United States)

Damora Therapeutics is an innovative biotechnology company that aims to fundamentally redefine care for people with hematologic disorders. We are advancing a new generation of biologics to treat mutant calreticulin-driven myeloproliferative neoplasms, including essential thrombocythemia and myelofibrosis, where there is significant medical need for new disease-modifying treatments. With multiple programs with best-in-class potential on track to enter clinical development in 2026, our goal is to rapidly bring forward optimized treatments with broad mutation coverage and exceptional convenience to dramatically improve patient outcomes. This is a unique opportunity to join a science-driven company at a formative stage, where early clinical data will directly shape development strategy and drive long-term value. The right candidate will join a team with significant early- and late-stage development experience, with the goal of quickly moving through dose escalation/expansion into pivotal trials. The Role The Director/Senior Director, Drug Product will report to the SVP, Technical Operations and will be responsible for leading formulation and process development, technical transfer, and manufacturing of drug product (monoclonal antibodies) into vial and/or prefilled syringes (PFS). This individual will lead phase-appropriate development efforts including optimization, characterization, validation, technical transfer, and routine manufacturing of drug product processes at Contract Development Manufacturing Organizations (CDMOs). This role will be a key contributor within Technical Operations at Damora. The successful candidate will be a confident process specialist with a proven track record in managing and leading biologic (monoclonal) programs through development and in support of licensure and commercialization. What You'll Do Lead the drug product development strategy and execution enabling consistent, high-yielding, high-purity, and scalable processes for vials and prefilled syringes (PFS). Develop robust, scalable formulations and drug product manufacturing processes to produce clinical trial material (CTM) while ensuring product quality Oversee technical activities at drug product CDMOs including technology transfer, CTM production, process troubleshooting, QbD and PAR studies, risk assessments, registration batch production, and process validation Responsible for technical leadership in technical issue resolution with CDMO partners, including formulation challenges, technical transfer, design of experiments, and interpretation of results Provide technical and scientific direction to CDMOs and external laboratories to ensure project deadlines and performance standards are met Lead the development/optimization of scalable, efficient, and cost-effective processes; lead the design of experiments incorporating Quality by Design (QbD) into the process characterization Lead process validation activities and strategies including establishing and evaluating process characterization plans, overseeing execution at CDMO, reviewing and approving CDMO reports Oversee the preparation of manufacturing batch records, technical reports, data summaries and CMC related documents required for various regulatory submissions Coordinate with Quality and Supply Chain teams to ensure timely manufacture and release of drug product lots by leading technical reviews of batch records, deviations, change controls, and nonconformance investigations; proactively identify and mitigate risks related to clinical supply Manage related SOPs, change controls, deviations and CAPAs with thorough knowledge of Good Manufacturing Practices Serve as the drug product subject matter expert for program teams, due diligence activities, and CMO selection, management, and audits Ensure adherence to applicable regulations and guidelines, including FDA, EMA, ICH, GCP, and GMP Provide person-in-plant support for drug product manufacturing Author and review CMC sections of regulatory filings, including INDs, IMPD/IND amendments, and NDA/MAA submissions What You'll Bring Masters or PhD (preferred) in engineering, chemistry, biological science, or another relevant field 12 years of relevant biopharmaceutical industry experience with experience in process development, technical transfer, and implementation of biologics (monoclonal antibodies preferred) for subcutaneous administration Expertise in process design and development approaches with a thorough understanding of regulatory requirements for both vials and syringes Knowledge of needle safety devices, autoinjectors, and on-body devices preferred. Demonstrated ability to successfully work with and influence CDMOs while maintaining a positive working relationship Proven leadership in developing and optimizing formulations and processes, scaling them up for implementation, and transferring them to CDMOs Ability to work/lead in a dynamic group that takes a multi-disciplined team approach to executing and achieving departmental and corporate goals Hands‑on, roll‑up-your‑sleeves approach with strong drive for results Demonstrated communication, problem-solving, leadership, and negotiation/decision‑making skills Ability to think outside of the box and challenge the status quo Natural entrepreneurial spirit with unrelenting dedication to delivering results Desire to work in a fast‑paced, innovative environment Natural collaborator who enjoys working on a cross‑functional team Hybrid in the Boston area Dynamic, interactive, fast-paced and entrepreneurial environment May require up to 20% travel Benefits At Damora Therapeutics, we offer competitive compensation and thoughtfully designed total rewards aligned with industry benchmarks. We believe in rewarding impact and building meaningful ownership for our team. J-18808-Ljbffr

Gym GM: Growth Leader Free Membership (Tampa)

EōS Fitness is bold, upbeat, and motivating. Not only in our fitness routines, but in our work environment as well. Like our members, our employees know how to rise to a challenge and handle it head on. EōS Fitness’ Core Purpose is to create loyal, lifelong fans and exercise practitioners. To achieve this purpose, our Core Values are: Take Personal Responsibility, Be Optimistic & Have Fun, Learn & Grow, Be A Team Player, and Fight Hard To Win. Core Purpose: To create loyal, lifelong fans and exercise practitioners. EōS Fitness is seeking a highly motivated and sales driven leader to take on the role of General Manager. Reporting to the District Sales Manager, the General Manager must be passionate about sales and dedicated to helping members achieve their health and wellness goals. As General Manager, you will work to improve sales, overall processes, and develop a team of leaders to do the same. You and your team will create connections with prospective members, facilitate their membership journey, and ensure their success. An ideal candidate must have a passion for fitness, demonstrate a drive for success, and a history of commitment, delivering results and motivating clients. Position Purpose: Develop a team that delivers exceptional customer experience and hits business objectives. Core Purpose: To create loyal, lifelong fans and exercise practitioners. Responsibilities: Hiring, training, scheduling, and supervising staff members, including Assistant General Managers and Fitness Consultants. Effectively communicate goals, expectations, and procedures to staff members, ensuring everyone understands their roles and responsibilities. Set and achieve membership and revenue goals, track KPIs, and develop strategies to increase membership retention and new sign-ups. Provide constructive feedback to staff members on their performance, using clear and specific language to highlight areas of strength and areas for improvement. Ensuring high-quality customer service by addressing member concerns or complaints, managing membership inquiries, and resolving issues promptly. Engage with members in a friendly and approachable manner, actively listening to their needs and concerns, and providing clear and helpful responses. Ensuring compliance with health and safety regulations, maintaining proper certifications, and implementing safety protocols. Supervising the maintenance and cleanliness of the facility, including equipment, locker rooms, and common areas. In the event of emergencies or unexpected disruptions, communicate calmly and clearly with staff and members, providing necessary instructions and updates to ensure their safety and well-being. Qualifications: 2 years of sales management experience. 3-4 years of customer service experience. Prior experience or strong interest in the fitness industry. Strong communication skills, both verbally and in writing, for interacting with employees, management, and vendors. Excellent relationship building and influencing skills with people at all levels and in all functions. Strong detail orientation; systematic and thorough approach to problem solving; and good time management, organizational, and record-keeping skills. Excellent MS Office skills. And, of course, someone who embraces our Core Values! Requirements: Must successfully pass background check. CPR certification required within 30 days of hire. Ability to work in a gym setting; move about club floors and rooms; communicate with employees, members, and the public Ability to access and operate the Company computer system including preparing documents, entering data into computer system, read reports from a computer data base or email system Ability to bend routinely and repetitively to lift more than 40 lbs. Salary Pay Range $65,000—$70,000 USD Benefits and Perks: A highly energetic and collaborative team. A management team that cares about your professional development. Free membership for you and plus one family member. Discounted Personal Training, and merchandise – including supplements. Employee referral program. Daily Pay offered - access your funds before payday. Competitive pay plus vacation, holiday, and sick pay.* Group Health, dental, vision, Supplemental Life, and Employee Assistant Program are offered 401(k) Company matching Personal education growth options with Sophia Learning. * Based on eligibility of tenure and full-time vs. part-time employment. EōS Fitness is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender identity, sexual orientation, national origin, age, disability, or any other legally protected status. To view more information on our CCPA policy, click HERE . EEO is The Law - click here for more information Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled EōS Fitness participates in the government eVerify program. Please review the details of this program by clicking here . We endeavor to make this site accessible to any and all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process, please contact the Recruiting Help Line at [email protected] or by calling 949.309.4182. To check on the status of your application, please visit the Greenhouse Candidate Portal at my.greenhouse.com for updates. J-18808-Ljbffr

Managing Director of Technology - St Louis (St. Louis)

Managing Director of Technology - St Louis St Louis Location: Remote (U.S. or Canada) Type: US Applicants – Full-Time; Canadian Applicants – Independent Contractor About Human Agency We're scaling rapidly and have a growing pipeline of opportunities that demand exceptional talent across disciplines. Our mission is to bring on individuals, from creative producers to technical experts to entrepreneurial leaders, who can help us realize this next chapter of growth. We are a company of doers. Leaders roll up their sleeves, teams work flat, and everyone contributes to what ships. Titles don't insulate us from feedback or basics. We invite critique, learn quickly, and keep raising the bar. The best ideas win here, no matter where they come from, because clients trust us to deliver the strongest outcomes every time. Our clients' missions, products, and bottom lines are sacred. We immerse ourselves in their world, becoming stewards of their goals and partners in solving big problems. Every product, strategy, or asset we create must be both beautiful and functional; practical, usable, and designed for real-world impact. Humans are our most valuable resource, and we only grow by hiring people who push us forward. Across strategy, engineering, design, data, and operations, we seek out teammates who raise the bar and make us better. Always hire up, never down. We partner with organizations of all sizes to explore, design, and implement AI strategies that are secure, scalable, and human-centered. We believe AI should amplify human potential, not replace it, and we build with that conviction in every engagement. From advisory and tooling to implementation and education, we meet clients where they are and help them integrate AI in ways that align with their mission and values. Our goal is to empower teams to work smarter, move faster, and unlock new possibilities through thoughtful, responsible innovation. And through it all, we lead with purpose, love, and adventure. We do meaningful work with people we care about, and we make the ride an adventure worth taking. Because at Human Agency, who we are and how we work are one and the same. The Opportunity Human Agency is an AI-native consultancy that builds, ships, and operates alongside our clients. We don’t advise from the sideline — we embed inside enterprise organizations and deploy production AI systems that do real work. Our current anchor engagement is inside one of the largest privately held construction enterprises in the United States — LLM orchestration, document intelligence, workflow automation, enterprise integration. Not strategy decks. Not innovation labs. Systems that run. We need a Managing Director of Technology to own the technical side of the house as we scale Human Agency. That means leading client delivery, making architecture calls, building the engineering team, and being the technical voice in rooms with C-suite executives. You’ll report to the Managing Partner and work as a peer on strategy with the Managing Director of AI — but the technical execution, the team, and the platform are yours. This role requires someone who can move between writing production code and presenting to a client’s CEO in the same week. If that sounds like whiplash, this isn’t the right fit. If that sounds like Tuesday, keep reading. What You’ll Do Lead technical delivery for enterprise clients. You’re the most senior technical person in the room on our biggest engagements. You decide what’s feasible, design the architecture, and make sure it ships. When a client executive asks “can we do this?” — you’re the one who answers. Build how we deliver, not just what we deliver. One client engagement works because of talented people and brute effort. Ten engagements work because of systems. You design the repeatable model — how we scope, staff, build, and deploy — so the team can run engagements without you in every meeting. That means building discovery frameworks, reference architectures, deployment templates, and evaluation routines that actually get used. Hire and develop the engineering team. You set the bar, own the pipeline, and make the calls on who joins. We need people who can build with high autonomy in ambiguous environments, and you know how to find them. You also know how to make good engineers better through architecture guidance, code review, and honest feedback. Own platform and infrastructure decisions. Build vs. buy, tooling, deployment, security — you make the calls. A Principal Engineer handles day-to-day infrastructure execution; you set priorities and architectural direction. Shape our AI strategy through the lens of what actually ships. You have real opinions on LLM orchestration, RAG, agents, evaluation, and fine-tuning — formed by building things, not reading about them. You decide which technical bets we make and which we skip, based on what creates value for clients, not what looks good on a slide. What We’re Looking For You’ve built and shipped AI/ML systems in production. Not prototypes. Not demos. Things that run and that people depend on. You’ve hired and led a technical team — at least 5 people, ideally more. You’ve seen what breaks when a team grows and you’ve fixed it. You can explain a technical trade-off to a non-technical executive in a way that helps them make a decision. You’ve done this in high-stakes settings. You have strong opinions on AI architecture grounded in hands‑on experience — and you change those opinions when the evidence says to. You’re comfortable in the weeds. When something is broken or a team is stuck, you get in and help, not schedule a meeting about it. You know your way around cloud infrastructure and engineering practices well enough to make platform calls with confidence. Bonus points for: you’ve scaled a startup or early‑stage company before — built the team, built the systems, lived through the growing pains; experience in a services or consultancy model (SOWs, staffing, client delivery); a network of engineers you’ve worked with and would hire again. You Should Apply If You’d rather build AI systems than talk about AI strategy You want to own a technical organization, not manage a lane inside someone else’s You’re comfortable making big decisions with imperfect information — and owning the outcome You want to work somewhere with real revenue, real clients, and real problems to solve You’re energized by building a company — not just writing code, but shaping how the whole thing works You Should Not Apply If You want a CTO‑like title with a strategy focus and minimal hands‑on building You’re uncomfortable getting into production‑level detail when the situation calls for it You expect an established engineering org with playbooks, processes, and a support structure already in place You’d rather delegate technical depth than engage directly Your experience is solely in product companies and you’re not interested in building for clients Considerations Education: Bachelor’s degree or equivalent experience; advanced degrees are a plus but not required Ethics: Commitment to responsible AI practices — transparency, human oversight, privacy Travel: Periodic (10–20%) for client work, team offsites, and events Location: Remote-friendly; U.S. or Canada, with preference for EST timezone alignment Why Join Human Agency We’re profitable, growing, and building AI systems that run in production for billion‑dollar companies. The team is small, the clients are real, and the work matters. The work is real and the opportunity is massive. We’re building a company — the systems, the team, the delivery model, the culture — and we need someone to own the technical side of that build. If you’re the kind of person who’d rather build the engine than describe the engine, we want to talk. Equal Opportunity Commitment Human Agency is an Equal Opportunity Employer. We value diverse perspectives and are committed to building inclusive, high‑performing teams where everyone can do their best work. J-18808-Ljbffr

Chief Compliance Officer Global (New York)

About the Job zerohash is seeking a Global Chief Compliance Officer, who will help shape and lead zerohash global compliance leadership team and posture and orchestrate adherence to industry-leading compliance standards across all supported geographies. This broad role will be responsible for leading zerohash’s compliance, regulatory and licensing processes. This is a supervisory position that will manage a global team. The ideal candidate leads by example and is a strategic thinker, a great communicator, and has the ability to influence through respect and trust. You will report directly to the Co-President. Responsibilities Manage the full Global Compliance function Lead all zerohash licensing processes Maintain an understanding of global regulations; regulatory and compliance requirements; and developments relative to zerohash’s business as well as provide regional compliance support for other teams within zerohash Design, implement, and manage customer onboarding and ongoing compliance processes, including anti-money laundering (AML) and sanctions, in conformity with regulatory requirements Develop and maintain excellent relationships with regional regulators Manage regulatory filings within the regions Manage regional regulatory examination responses and regulatory interactions Requirements 10 years of Compliance experience, including AML, sanctions and financial crimes compliance, within a financial services company or Fintech startup Experience working in and scaling international expansion of a Fintech startup Demonstrated ability to build and oversee complex programs in a dynamic growth-minded environment Experience working with regional financial regulators, to include exam management Legal/law degree preferred Independent, hardworking and driven with experience accomplishing tasks within a delegated environment Strong time management skills and ability to execute tasks within tight deadlines Strong verbal and written communication skills Strong interpersonal skills necessary to communicate effectively with regulators and work effectively with colleagues across regions and business units Strong familiarity with Google Suite and Microsoft Suite products Crypto experience a plus Benefits Healthcare Insurance: zerohash covers roughly 100% of employee premiums as well as a portion of spouse/children (U.S. only) Vision & Dental Insurance (U.S. only) Chance to earn equity Maternity & Paternity leave (after 6 months) WeWork All Access Membership WFH Yearly Stipend L&D Yearly Stipend (after 6 months) J-18808-Ljbffr

Senior Director, Product Management (Dallas)

Overview At PowerSchool, we are a dedicated team of innovators guided by our shared purpose of powering personalized education for students around the world. From the central office to the classroom to the home, PowerSchool supports the entire educational ecosystem as the global leader of cloud-based software for K-12 education. Our employees make it all possible, and a career with us means you are joining a successful team committed to engaging, empowering, and improving the K-12 education experience everywhere. Team Overview Our Product team leads the direction, coordination, output, quality, and enhancements to PowerSchool’s product portfolio. This dynamic, multi-functional team ensures the effective rollout of new products across the platform, packages and positions products to appeal to consumers, and helps set the future direction and pace of innovation in our organization. Responsibilities The Senior Director of Product Management is responsible for guiding the overall roadmap for the Product portfolio of PowerSchool. The Senior Director is responsible to leading and managing the business analysis, roadmap development and guiding all product activities for the Product portfolio. Captures, articulates and manages requirements and use case documentation. The Product Management team is critical in full lifecycle product planning, delivery, and marketing with the end user in mind. Your day-to-day job will consist of: Lead the development and implementation of the Classroom Portfolio roadmap. Manage a team of product management professionals. Assess needs and opportunities for Classroom products through research and feasibility analysis. Manage, gather, and analyze competitive intelligence data for product lines. Participate in product modification, support cost reduction, margin analysis, forecasting, product positioning and pricing strategies. Ensure roadmap plans are aligned with portfolio vision, business objectives, market needs, and competitive environment. Senior product expert positioned as a key resource with Clients, prospects and partners. Work with Sales and Project Management to gather/document business requirements. Lead the writing and curation of clear, detailed business requirements for product and project initiatives. Work effectively within and across Classroom data operations and engineering teams to execute projects and roadmap items. Assist in creating go to market strategies. Stay abreast of changing industry regulations affecting product development. Qualifications Minimum Qualifications Minimum of 12 years of relevant and related work experience. Bachelor’s degree or equivalent, or equivalent years of relevant work experience. Travel occasionally, up to 15-20%, for key moments such as team summits, training, customer meetings, company events, etc., with increased frequency during peak periods based on business demands. This position is subject to company on call policies which constitutes working hours outside of the normal workday as needed. Manage and lead others effectively, growing the skill set and capabilities of the team holistically and for each individual contributor. Solid understanding of Software Development Lifecycle models. Preferred Qualifications Specialized knowledge. Understanding of K12 District needs for the classroom. Excellent written and verbal communication/presentation skills. Exhibit intelligent decisiveness. Manage multiple projects/products simultaneously. Excellent customer-facing skills. Excellent ability to listen for both what is and is not being said - seek to understand before being understood. Able to operate within a structured environment, but willing to foresee and/or solve problems when they arise. Compensation & Benefits PowerSchool offers the following benefits: Comprehensive Insurance Coverage (including Medical, Dental, Vision, Pharmacy benefits, Life Insurance and AD&D) Flexible Spending Accounts and Health Savings Accounts Short-Term Disability and Long-Term Disability Comprehensive 401(k) plan Generous Parental Leave Unrestricted paid time off (known as Discretionary Time Off - DTO) Wellness Program, including ClassPass & Employee Assistance Program Tuition Reimbursement Optional Benefits: Pet Insurance, Identity Theft Protection, Student Debt Repayment Program and Prepaid Legal coverage A reasonable estimate of the base compensation range for this position is $144,900 - $241,100 USD. This compensation range is specific to the United States and it incorporates many factors including but not limited to an applicant's skills and prior relevant experience and training; licensures, degrees, and certifications; internal equity; internal pay ranges; and market data/range parameters. EEO Commitment PowerSchool is committed to a diverse and inclusive workplace. PowerSchool is an equal opportunity employer and does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Our inclusive culture empowers PowerSchoolers to deliver the best results for our customers. We not only celebrate the diversity of our workforce, we celebrate the diverse ways we work. If you have a disability and need an accommodation regarding our recruiting process, please let us know by emailing [email protected]. J-18808-Ljbffr

General Manager (San Antonio)

Benefits and Compensation The highest paying GM roles can earn over $200,000 in 2026. Base salary for General Managers: $75,000 - $80,000. Short‑term monthly bonus and annual long‑term bonus potentially adding $35,000 - $150,000 per year. Health insurance covering 100% of health, dental, and vision for all managers; annual benefit value $6,400. Up to 20 days paid vacation/personal days per year. Free meals at Pluckers (annual value $3,900). Career Growth Pluckers is opening 20 new restaurants across Texas over the next four years, creating opportunities for 20 new General Managers and 120 new Assistant Managers. Within 6-12 months you can become a General Manager. Our Area Managers earn $175,000 - $400,000 per year, depending on the number of restaurants overseen. Progression to Area Manager requires completing a 16‑week training program, gaining experience as an Assistant General Manager, and mastering the General Manager role. Training and Development 16‑week Coach training program (Pluckers University) covers culture, expectations, and the Pluckers Way. Ongoing Leadership Development Programs support professional and personal growth for all Coaches. Company Culture Pluckers is based in Austin and has been named the Best Restaurant to Work For five times; it also ranks in the Top 25 Businesses Overall to Work For by the Austin Business Journal. Our management team is called “Coaches” and focuses on a people‑first mindset, providing clear expectations, feedback, and goals. Coaches are expected to lead by example, working early or late as needed to meet high standards of guest service. Qualifications Professional attitude and appearance. Can‑do, team‑oriented mindset. Intelligence, analytical skills, assertiveness, passion, energy, tenacity, and the ability to inspire followership. Ability to meet Pluckers’ high standards of guest service. Salary $125,000 - $200,000 per year. J-18808-Ljbffr